Results 141 to 150 of about 27,443,428 (376)
A working model for cytoplasmic assembly of H/ACA snoRNPs
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
"In this edition the text has again been revised. No great changes have been made, but there have been some additions to the text and illustrations"-Pref. ; "Printed in Great Britain." ; Some plates accompanied by guard sheet with descriptive letterpress. ; Mode of access: Internet.
openaire +3 more sources
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican+7 more
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The Fight against Tuberculosis in the Light of the Experience Gained in the Successful Combat of Other Infectious Diseases [PDF]
Robert Koch
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Novel and unscrutinized immune entities of the zebrafish gut
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil+5 more
wiley +1 more source
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona+4 more
wiley +1 more source
Fibrocystic Disease of the Pancreas in AdolescenceHeld at the Postgraduate Medical School (Hammersmith Hospital) on March 3, I954. The report was assembled by Dr. Bernard Lennox. The sections were prepared under the direction of Mr. J. Griffin and the photomicrographs by Mr. C. A. P. Grahame. [PDF]
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