Results 261 to 270 of about 26,337,030 (428)

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Editorial: Contemporary Medicine: Making Sense of Implementation Models and Methods

Frontiers in Medicine, 2022
Michele M. Ciulla, Michele M. Ciulla, Ugo Cioffi   +2 more
doaj   +1 more source

Note On Warty Disease Of The Potato [PDF]

, 1908
A. W. Borthwick
openalex   +1 more source

Clinical diagnosis of Alzheimer's disease

Neurology, 1984
G. Mckhann, D. Drachman, M. Folstein, R. Katzman, D. Price, E. Stadlan   +5 more
semanticscholar   +1 more source

Modeling and analysis of infectious diseases based on behavioral game theory on two-layered networks under media coverage. [PDF]

PLoS One
Wang J, Zeng R, Chang X.
europepmc   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Coeliac Disease [PDF]

BMJ, 1948
openaire   +4 more sources

DISEASES AND CONDITIONS TO WHICH THE REST TREATMENT IS ADAPTED [PDF]

, 1892
WHARTON SINKLER
openalex   +1 more source

Genetically-determined variation in CRP impacts disease activity assessment in rheumatoid arthritis. [PDF]

Rheumatology (Oxford)
Riley TR, Wheeler AM, Cannon GW, Sauer B, Wysham KD, England BR, Wipfler K, Michaud K, March M, Damrauer SM, Verma A, George MD, Mikuls TR, Baker JF.   +13 more
europepmc   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source