Results 271 to 280 of about 10,094,215 (299)
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Meniere's disease

Nature Reviews Disease Primers, 2016
Menière’s disease causes paroxysmal rotatory vertigo, due to endolymphatic hydrops, an accumulation of endolymph in the endolymphatic space of the labyrinth. Its major symptoms are attacks of rotatory vertigo lasting minutes to hours, with unilateral hearing loss, tinnitus and aural fullness.
Tsutomu, Nakashima   +8 more
openaire   +3 more sources

Disease model: Parkinson's disease

Trends in Molecular Medicine, 2003
Parkinson's disease (PD) is a progressive neurodegenerative disorder that is primarily characterized by the degeneration of dopaminergic neurons in the nigrostriatal pathway. The pathology of PD is typified by the presence of cytoplasmic inclusions (Lewy bodies) containing alpha-synuclein and ubiquitin.
Shun, Shimohama   +3 more
openaire   +2 more sources

Periodontal Disease and Cardiovascular Disease

Journal of Periodontology, 1996
It is our central hypothesis that periodontal diseases, which are chronic Gramnegative infections, represent a previously unrecognized risk factor for atherosclerosis and thromboembolic events. Previous studies have demonstrated an association between periodontal disease severity and risk of coronary heart disease and stroke.
James, Beck   +4 more
openaire   +3 more sources

Wilson’s Disease

Clinical Gastroenterology and Hepatology, 1998
Wilson's disease is an autosomal, recessive-inherited disorder of impaired biliary copper excretion that results in the accumulation of copper in various organs including the liver, the cornea and the brain. The Wilson's disease gene on chromosome 13 codes for a copper transporting P-type ATPase-ATP7B.
openaire   +4 more sources

Mitochondrial disease

The Lancet, 2006
Defects of mitochondrial metabolism cause a wide range of human diseases that include examples from all medical subspecialties. This review updates the topic of mitochondrial diseases by reviewing the most important recent advances in this area. The factors influencing inheritance, maintenance and replication of mtDNA are reviewed and the genotype ...
openaire   +3 more sources

Sylvest's Disease (Bornholm Disease)

New England Journal of Medicine, 1954
THERE appears to be a remarkable degree of freemasonry amongst epidemiologists. I have visited many countries and have invariably experienced friendliness and cordiality from those of a like mind.
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Whipple's disease

Annals of the Rheumatic Diseases, 2002
Whipple's disease is a chronic systemic bacterial infection that predominantly affects middle-aged men. Antimicrobial therapy is curative. The causative agent has been identified as Tropheryma whippelii. A PCR-based diagnostic test is now available and is particularly useful in patients with early-stage or atypical disease.
openaire   +5 more sources

Kienböck's Disease

Hand Clinics, 1986
Kienbock's disease (lunate malacia) is an unusual but not rare cause of wrist pain. It is manifested by avascular necrosis and subsequent disintegration of the lunate. Despite recognition of this disease entity for the past 70 years, its cause is still debated.
openaire   +3 more sources

Huntington's Disease

Seminars in Neurology, 2007
Huntington's disease is an autosomal-dominant, progressive neurodegenerative disorder with a distinct phenotype, including chorea and dystonia, incoordination, cognitive decline, and behavioural difficulties. Typically, onset of symptoms is in middle-age after affected individuals have had children, but the disorder can manifest at any time between ...
openaire   +3 more sources

Caroli's disease

World Journal of Surgery, 1984
AbstractIn 1958, Caroli [1, 2] was the first to describe congenital dilatations of intrahepatic bile ducts concerning a segment, a sector, a lobe, or both halves of the liver. Sometimes the dilatations are associated with congenital hepatic fibrosis as described in 1954 by Grumbach [3], dilatations of biliary ductules (biliary angiomatosis), and ...
M, Mercadier   +4 more
openaire   +3 more sources

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