Mapping Hsp104 interactions using cross‐linking mass spectrometry
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal+3 more
wiley +1 more source
Parental liver disease mortality is associated with unfavorable outcomes in patients with alcohol-associated hepatitis. [PDF]
Tu W+20 more
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We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei+6 more
wiley +1 more source
Metabolic Dysfunction-Associated Steatotic Liver Disease Is Associated With Accelerated Brain Ageing: A Population-Based Study. [PDF]
Wang J+6 more
europepmc +1 more source
Advancements in Biomarkers for Early Detection and Risk Stratification of Cardiovascular Diseases-A Literature Review. [PDF]
Nazir A+7 more
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Cardiovascular mortality of 40-69-year-olds in Sri Lanka from 1980 to 2010: a birth cohort analysis by age and sex. [PDF]
De Silva D+5 more
europepmc +1 more source
Are your kidneys ok? Detect early to protect kidney health. [PDF]
Vassalotti JA+12 more
europepmc +1 more source
Comparing Viet Nam's national climate strategy's effectiveness in mitigating infectious diseases against other OECD countries in South-East Asia. [PDF]
Dunsford C+4 more
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Adherence to <i>a priori</i> and a posteriori dietary patterns and risk of Parkinson's disease: a systematic review and meta-analysis of observational studies. [PDF]
Zhang R, Shu L, Zhu Q, Li N.
europepmc +1 more source
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