Results 171 to 180 of about 13,421,695 (264)

Massachusetts state nutrition physical activity and obesity profile [PDF]

Many American communities lack environments that could support healthy diets and regular physical activity. Healthy dietary and physical activity practices can lower the risk for heart disease, type 2 diabetes, and some cancers.1,2In addition, excess ...

core  

Comparative evaluation of disease activity measures for adult-onset Still's disease: a multicentre, retrospective, cohort study. [PDF]

RMD Open
Vordenbäumen S, Filla T, Friedrich R, Blank N, Ernst D, Henes J, Keyßer G, Klemm P, Krusche M, Meinecke A, Rech J, Schulz N, Petzinna SM, Pankow A, Schäfer VS, Pfeil A, Klapa S, Pongratz G, Feist E, Kernder A.   +19 more
europepmc   +1 more source

Sugar‐Sweetened Beverage Consumption and Lipid Profile: More Evidence for Interventions

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Elena V. Kuklina, Sohyun Park
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Wyoming state nutrition physical activity and obesity profile [PDF]

Many American communities lack environments that could support healthy diets and regular physical activity. Healthy dietary and physical activity practices can lower the risk for heart disease, type 2 diabetes, and some cancers.1,2In addition, excess ...

core  

Circulating microRNA expression profiles as biomarkers of disease activity in multiple sclerosis. [PDF]

Mult Scler J Exp Transl Clin
Vigiser I, Zeevi Y, Piura Y, Kolb H, Golan M, Karni A, Regev K.   +6 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Association of Disease Activity and Socioeconomic Factors With Physical Activity in Patients With Systemic Lupus Erythematosus. [PDF]

ACR Open Rheumatol
Gold HT, Giunta I, Kim J, Li Y, Buyon JP, Izmirly PM, Masson M, Saxena A, Belmont HM, Tseng CE, Anthopolos R.   +10 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Low-Density Granulocytes Link to Disease Activity, Organ Involvement, and Cytokine Production in Sjögren's Disease. [PDF]

Int J Mol Sci
Ning J, Jin Y, He S, Huang B, Guan L, He J.   +5 more
europepmc   +1 more source