Results 261 to 270 of about 12,421,057 (398)

The Burden of Chronic Disease

open access: yesMayo Clinic Proceedings: Innovations, Quality & Outcomes
Karen Hacker
semanticscholar   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Cardiovascular Disease Burden in Rural Central Asia: A Systematic Review of Epidemiological Trends and Mortality Patterns. [PDF]

open access: yesEpidemiologia (Basel)
Kassymkhan A   +8 more
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

The rare disease burden: a multidimensional challenge. [PDF]

open access: yesActa Biochim Pol
Cyske Z   +4 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Cerebral Small Vessel Disease Burden in Acute Ischemic Stroke and the Role of Physical Activity: Cross-Sectional Study. [PDF]

open access: yesBrain Behav
Damsbo AG   +11 more
europepmc   +1 more source

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