Results 281 to 290 of about 12,421,057 (398)

Table 4_Trends and cross-country inequality in the global burden of nutritional deficiencies in children, with projections to 2035: results from the Global Burden of Disease study 2021.docx

Shihao Zhuang (9931763), Meijiang Ruan (21804428), Qin Chen (44010), Qiaomei Wang (1710562), Ting Chen (15205), Hao Wang (39217), Shanshan Liu (315561), Qiudan Chen (603628), Chengchen Zhang (7296182), Li Hong (426614)   +9 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Pakistan's rising cardiovascular disease burden associated with modifiable risk factors: an urgent appeal for evidence-driven action. [PDF]

Ann Med Surg (Lond)
Siddiqi AK, Mubashir E, Cheema AAA, Noshab M, Naeem M.   +4 more
europepmc   +1 more source

Carga de enfermedad atribuible a las afecciones inmunoprevenibles en la población infantojuvenil española Disease burden due to vaccinable diseases in the Spanish population aged less than 15 years old

, 2004
Marta Haro Cortés, Joaquín Pereira, Isabel Peña‐Rey, Ricard Gènova, Carmen Amela   +4 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Analysis of disease burden and future trends of ischemic heart disease in China and globally, 1990-2023. [PDF]

PLoS One
Zhang Z, Yue G, Wang L.
europepmc   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Serum Lactate Dehydrogenase as a Biomarker of Disease Burden and Chemotherapy Response in Canine High-Grade Multicentric Lymphoma. [PDF]

Vet Sci
Bitencourt RC, Garcia MF, Cabral APM, Gorenstein TG, Lesbon JCC, Anai LA, Fukumasu H, Horta RDS, de Nardi AB, Santana AE.   +9 more
europepmc   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source