Results 291 to 300 of about 12,421,057 (398)

Wealth creation and disease burden: Evidence from Nigeria based on a Bayesian-VAR approach. [PDF]

PLoS One
Lopreite M, Zhu Z.
europepmc   +1 more source

Alzheimer's disease biomarker burden in primary motor cortices is associated with poorer dexterity performance [PDF]

Lily Eliza Gupta, Yue Ma, Akshay Kohli, Kao Lee Yang, Jennifer M. Oh, Tobey J. Betthauser, Nathaniel A. Chin, Ozioma C. Okonkwo, Mary‐Elizabeth Pasquesi, Veena A. Nair, Vivek Prabhakaran, Shi‐Jiang Li, Barbara B. Bendlin   +12 more
openalex   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Expert Consensus Statement on the Disease Burden and Vaccination for Respiratory Syncytial Virus Infection in Adults. [PDF]

Tuberc Respir Dis (Seoul)
Choi JY, Rhee CK, Hwang YI, Moon JY, Yoo KH, Yoon HK.   +5 more
europepmc   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Systematic analysis of global ischemic heart disease and hypertensive heart disease burden, 1990-2021: projections to 2050. [PDF]

BMC Public Health
Li S, Liu Y, Liu C.
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

A Comprehensive Patient-Centric Analysis of Disease Burden, Treatment Challenges, and Unmet Needs in Behçet's Disease: Insights from a Large Cohort Study. [PDF]

Medicina (Kaunas)
Tharwat S, Abdalla IMIA, Elhefnawi MAF, Abutaleb AMM, Zein DM, Abdelmaksoud AAI, Elmetwalli RS, Elkilany HM, Abdelaziz RMM, Nassar MK.   +9 more
europepmc   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Cardiovascular disease burden in the homeless population. [PDF]

Open Heart
Korukonda S, Erukulla N, Harris JR, Kovuri P, Wilcox KT.   +4 more
europepmc   +1 more source