Results 61 to 70 of about 2,559,167 (303)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Fuelling walking and cycling: human powered locomotion is associated with non-negligible greenhouse gas emissions

Scientific Reports, 2020
Reducing motorized transport and increasing active transport (i.e. transport by walking, cycling and other active modes) may reduce greenhouse gas (GHG) emissions and improve health. But, active modes of transport are not zero emitters.
Anja Mizdrak, Linda J Cobiac, Christine L Cleghorn, Alistair Woodward, Tony Blakely   +4 more
doaj   +1 more source

Estimating the changing burden of disease attributable to high systolic blood pressure in South Africa for 2000, 2006 and 2012

South African Medical Journal, 2022
Background. Ongoing quantification of trends in high blood pressure and the consequent disease impact are crucial for monitoring and decision-making. This is particularly relevant in South Africa (SA) where hypertension is well-established.
B Nojilana, N Peer, N Abdelatif, A Cois, A E Schutte, D Labadarios, E B Turuwa, R A Roomaney, O F Awotiwon, I Neethling, R A Roomaney, V Pillay-van Wyk, D Bradshaw   +12 more
doaj   +1 more source

The journey from genetic predisposition to medication overuse headache to its acquisition as sequela of chronic migraine [PDF]

, 2018
Migraine remains one of the biggest clinical case to be solved among the non-communicable diseases, second to low back pain for disability caused as reported by the Global Burden of Disease Study 2016.
Martelletti, Paolo
core   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior, Edmara Bazoni Soares Maia, Soad Fuentes‐Alabí, Courtney E. Sullivan, Monnie Abraham, Mauricio Maza, Liliana Vásquez Ponce, Regina Aparecida Garcia Lima   +7 more
wiley   +1 more source

Estimating the changing burden of disease attributable to high sodium intake in South Africa for 2000, 2006 and 2012

South African Medical Journal, 2022
Background. Elevated sodium consumption is associated with increased blood pressure, a major risk factor for cardiovascular and chronic kidney disease. Objectives.
B Nojilana, N Abdelatif, A Cois, A E Schutte, E Wentzel-Viljoen, E B Turuwa, R A Roomaney, O F Awotiwon, I Neethling, R Pacella, V Pillay-van Wyk, D Bradshaw   +11 more
doaj   +1 more source

COPD: Optimizing Treatment [PDF]

, 2015
A guideline update and an expanded armamentarium have many physicians wondering how best to treat patients with COPD. Chronic obstructive pulmonary disease (COPD) carries a high disease burden. In 2012, it was the 4th leading cause of death worldwide.1,2
Ahmed-Sarwar, Nabila, Holub, David C, Pierce, Deirdre P   +2 more
core   +1 more source

Analytic lymph node number establishes staging accuracy by occult tumor burden in colorectal cancer. [PDF]

, 2012
BACKGROUND AND OBJECTIVES: Recurrence in lymph node-negative (pN0) colorectal cancer suggests the presence of undetected occult metastases. Occult tumor burden in nodes estimated by GUCY2C RT-qPCR predicts risk of disease recurrence.
Barkun, Alan, Hyslop, Terry, Schulz, Stephanie, Waldman, Scott A., Weinberg, David S.   +4 more
core   +2 more sources

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

Review of the evidence for the potential impact and feasibility of substituting saturated fat in the New Zealand diet

Australian and New Zealand Journal of Public Health, 2013
Objective: To estimate the potential impact on cardiovascular health of modifying dietary intake of saturated fat across the New Zealand population, and whether this would be appropriate and feasible.
Rachel H. Foster, Nick Wilson
doaj   +1 more source