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Optimal disease eradication [PDF]

Environment and Development Economics, 2004
Using a dynamic model of the control of an infectious disease, we derive the conditions under which eradication will be optimal. When eradication is feasible, the optimal program requires either a low vaccination rate or eradication. A high vaccination rate is never optimal. Under special conditions, the results are especially stark: the optimal policy
Barrett, Scott, Hoel, Michael
core   +10 more sources

Spatiotemporal Distribution of PRRSV-1 Clades in Hungary with a Focus on the Era of Disease Eradication [PDF]

Animals
Porcine reproductive and respiratory syndrome (PRRS) is the cause of the most severe economic losses in the pig industry worldwide. PRRSV is extremely diverse in Europe, which poses a significant challenge to disease control within a country or any ...
Ádám Bálint, Szilvia Jakab, Eszter Kaszab, Szilvia Marton, Krisztián Bányai, Sándor Kecskeméti, István Szabó   +6 more
doaj   +2 more sources

Intervention-based stochastic disease eradication.

PLoS ONE, 2013
Disease control is of paramount importance in public health, with infectious disease extinction as the ultimate goal. Although diseases may go extinct due to random loss of effective contacts where the infection is transmitted to new susceptible ...
Lora Billings, Luis Mier-y-Teran-Romero, Brandon Lindley, Ira B Schwartz   +3 more
doaj   +5 more sources

Probiotic Supplementation for Treatment of Infection: A Double-Blind Randomized Clinical Trial [PDF]

The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2023
Background/Aims The effects of probiotic supplementation on Helicobacter pylori (H. pylori) eradication therapy are not completely understood. In this study, we investigated the effects of continuous probiotic administration on eradication rates ...
Na Rae Lim, Soo Yeon Choi, Woo Chul Chung   +2 more
doaj   +1 more source

Approach to Patients with Consecutive Eradication Failure [PDF]

The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2023
Helicobacter pylori (H. pylori) is associated with various gastrointestinal disorders, such as gastritis, peptic ulcers, mucosa-associated lymphoid tissue lymphoma, and gastric cancer.
Sung Eun Kim
doaj   +1 more source

Epidemiological and molecular investigations of a point-source outbreak of Dracunculus medinensis infecting humans and dogs in Chad: a cross-sectional study

The Lancet Microbe, 2022
Summary: Background: Dracunculiasis (also known as Guinea worm disease), caused by the Dracunculus medinensis nematode, is progressing towards eradication, with a reduction in cases from 3·5 million cases in the mid-1980s to only 54 human cases at the ...
Sarah Anne J Guagliardo, PhD, Elizabeth Thiele, PhD, Karmen Unterwegner, MPH, Ndoyengar Narcisse Nanguita, MPH, Laurès Dossou, MPH, Philip Tchindebet Ouakou, MD, Hubert Zirimwabagabo, MD, Ernesto Ruiz-Tiben, PhD, Donald R Hopkins, MD, Sharon L Roy, MD, Vitaliano Cama, DVM, Henry Bishop, BS, Sarah Sapp, PhD, Sarah Yerian, MPH, Adam J Weiss, MPH   +14 more
doaj   +1 more source

Community-based survey to assess seroprevalence of poliovirus antibodies in far-north Cameroon in 2020

Vaccine: X, 2022
Background: This study assessed seroprevalence of poliovirus antibodies in children from selected poliovirus high-risk areas of the Far North region of Cameroon which serves to monitor polio immunization program. Methods: This was a community-based cross-
Marie Claire Endegue, Carolyn Sein, Rocio Lopez Cavestany, Visalakshi Jeyaseelan, Tess Palmer, Gnakub Norbert Soke, Aissata Diaha, Basit Jafri, Bernardo A. Mainou, Harish Verma, Ondrej Mach   +10 more
doaj   +1 more source

Immunity to poliovirus in Afghanistan: A household sampling method for serological assessment based on geographical information systems

Geospatial Health, 2022
Afghanistan continues to experience challenges affecting polio eradication. Mass polio vaccination campaigns, which aim to protect children under the age of 5, are a key eradication strategy.
Amalia Mendes, Ari Whiteman, Benjamin Nygren, Brian Kaplan, Imtiaz Hussain, Sajid Soofi, Maureen Martinez, Noha H. Farag   +7 more
doaj   +1 more source

Current and future strategies for the treatment of chronic hepatitis C [PDF]

Clinical and Molecular Hepatology, 2021
Chronic hepatitis C infection is a major cause of liver disease and hepatocellular carcinoma worldwide. While hepatitis C has been treated for decades with some success, the introduction of direct acting antiviral agents has revolutionized the treatment ...
Omar Alshuwaykh, Paul Y. Kwo
doaj   +1 more source

Immunogenicity of two-dose and three-dose vaccination schedules with Sabin inactivated poliovirus vaccine in China: An open-label, randomized, controlled trial

The Lancet Regional Health. Western Pacific, 2021
Background: We assessed immunogenicity of three-dose and two-dose immunization schedules with a Sabin-strain inactivated poliovirus vaccine (sIPV) produced by one Chinese vaccine manufacturer. Methods: This was an open label, randomized, controlled trial
Yamin Wang, Qing Xu, Vishali Jeyaseelan, Zhifang Ying, Ondrej Mach, Roland Sutter, Ning Wen, Lance Rodewald, Changgui Li, Jie Wang, Hui Yuan, Zundong Yin, Zijian Feng, Aiqiang Xu, Zhijie An   +14 more
doaj   +1 more source