Results 31 to 40 of about 123,413 (291)
Peste des Petits Ruminants Infection among Cattle and Wildlife in Northern Tanzania
Emerging Infectious Diseases, 2013 We investigated peste des petits ruminants (PPR) infection in cattle and wildlife in northern Tanzania. No wildlife from protected ecosystems were seropositive.
Tiziana Lembo +10 more
doaj +1 more source
ERADICATION OF VACCINE-PREVENTABLE DISEASES [PDF]
Annual Review of Public Health, 1999 ▪ Abstract Eradication is the permanent reduction to zero of the worldwide incidence of infection caused by a specific agent as a result of deliberate efforts; intervention measures are no longer needed. To date, the only infectious disease that has been eradicated is smallpox.
openaire +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Is it possible to eliminate hepatitis C from the prisons of Catalonia, Spain, in 2021?
Revista Española de Sanidad Penitenciaria, 2019 Aim: Predict the elimination of chronic hepatitis C in Catalan prisons. Material and method: We analyzed the trend of the prevalence of HCV-RNA and anti-hepatitis C treatments prescribed in Catalonia in the period 2002-2016.
A Marco +6 more
doaj +1 more source
Proton Pump Inhibitor Switching Strategy after Failure of Standard Triple Therapy for Infection [PDF]
The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2020 Background/Aims It is still unknown whether cytochrome P450 (CYP) 2C19 polymorphisms influence Helicobacter pylori (H. pylori) eradication, especially in eastern Asia.
Jaeyoung Kim +2 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
The Lancet Regional Health. Western PacificSummary: Background: In June 2018, a type 1 circulating vaccine-derived poliovirus (cVDPV1) outbreak was declared in Papua New Guinea (PNG), resulting in a total of 26 paralytic confirmed cases.
William Pomat +11 more
doaj +1 more source
Eradicate first, or treat peptic ulcer disease?
SAGE Open Medicine, 2023 Background: Helicobacter pylori infection is very common worldwide, and about 10%–16% of these patients develop peptic ulcer disease. However, there is limited research on the impact of H. pylori eradication and peptic ulcer disease treatment sequencing.
Xinjue He, Lan Li, Chao Lu
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Animals, 2023 Peste des petits ruminants (PPR) is a burdensome viral disease primarily affecting small ruminants, which is currently targeted for eradication by 2030 through the implementation of a Global Control and Eradication Strategy (PPR GCES).
Camilla T. O. Benfield +7 more
doaj +1 more source