Results 131 to 140 of about 526,179 (300)

A Modular Mechanistic In Silico Model for In Vitro Transcription Process Yield and Product Quality Prediction

Biotechnology and Bioengineering, EarlyView.
ABSTRACT In vitro transcription (IVT) plays a critical role in the manufacture of mRNA vaccines and therapeutics. Optimizing mRNA yield and ensuring product quality, such as capping efficiency and integrity, are essential but mechanistically complex. This study presents a modular mechanistic model of the IVT process to advance scientific understanding ...
Keqi Wang, Keilung Choy, Eli Reiser, Jinxiang Pei, Hua Zheng, Aparajita Dasgupta, Fuqiang Cheng, Guogang Dong, Bhanu Chandra Mulukutla, Joshua Mannheimer, Carolyn Huang, Hooman Farsani, Wei Xie   +12 more
wiley   +1 more source

Improving the learning experience in an undergraduate course on microbial metabolism by using an illustrated story

Biochemistry and Molecular Biology Education, Volume 53, Issue 2, Page 131-141, March/April 2025.
Abstract In the classroom, metabolism is often approached and received as a mundane exercise in memorization. Teaching metabolism also faces the challenge of negative perceptions that can impede learning. We sought to improve the learning experience in an undergraduate lecture course on microbial metabolism by implementing an illustrated story that ...
James B. McKinlay, Katherine Kearns
wiley   +1 more source

Concurrent Rabies and Canine Distemper Outbreaks and Infection in Endangered Ethiopian Wolves

Emerging Infectious Diseases
Intensive disease surveillance in an endangered population of Ethiopian wolves provided evidence of concurrent outbreaks of rabies and canine distemper viruses in 2019, including co-infection in an individual animal.
Jorgelina Marino, Elizabeth F.R. Preston, Muktar Abute, Alo Hussein, Fekede Regassa, Asefa Deressa, Eric Bedin, Ashley C. Banyard, Anthony R. Fooks, Claudio Sillero-Zubiri   +9 more
doaj   +1 more source

1955 Summary of Disease Outbreaks [PDF]

Public Health Reports (1896-1970), 1956
C C, DAUER, G, SYLVESTER
openaire   +2 more sources

Counting cases, conserving species: addressing highly pathogenic avian influenza in wildlife

Biological Reviews, EarlyView.
ABSTRACT Highly pathogenic avian influenza (HPAI) has become a critical threat to wildlife, shifting from a seasonal epizootic to a persistent, year‐round panzootic with global consequences. Here, we summarise the origin, evolutionary mechanisms, and expanding host range of the current H5N1 virus (clade 2.3.4.4b) and assess its impact on wildlife. Over
Ulrich Knief, Sandra Bouwhuis, Anja Globig, Anne Günther, Wouter Courtens   +4 more
wiley   +1 more source

ESG Performance, Debt Financing, and R&D Output: Evidence From the Healthcare Sector

Business Strategy and the Environment, EarlyView.
ABSTRACT Amid growing calls for sustainability in the healthcare sector, this study examines how and under what conditions environmental, social, and governance (ESG) performance influences research and development (R&D) output. Although existing studies suggest that ESG performance enhances R&D output, the financial mechanisms that enable or constrain
Sarmad Ali, Oriana Ciani, Simone Ghislandi   +2 more
wiley   +1 more source

Bayesian inverse ensemble forecasting for COVID‐19

Canadian Journal of Statistics, EarlyView.
Abstract Variations in strains of COVID‐19 have a significant impact on the rate of surges and on the accuracy of forecasts of the epidemic dynamics. The primary goal for this article is to quantify the effects of varying strains of COVID‐19 on ensemble forecasts of individual “surges.” By modelling the disease dynamics with an SIR model, we solve the ...
Kimberly Kroetch, Don Estep
wiley   +1 more source

Disease outbreak in wildlife changes online sales of management items

One Health
Infectious diseases of wildlife cause human health hazards and economic losses. However, it is unclear how outbreaks affect human behaviour in relation to countermeasures against human–wildlife conflict.
Tomohiko Endo, Shinya Uryu, Keita Fukasawa, Jiefeng Kang, Takahiro Kubo   +4 more
doaj   +1 more source

On SARS type economic effects during infectious disease outbreaks [PDF]

Infectious disease outbreaks can exact a high human and economic cost through illness and death. But, as with severe acute respiratory syndrome (SARS) in East Asia in 2003, or the plague outbreak in Surat, India, in 1994, they can also create severe ...
Brahmbhatt, Milan, Dutta, Arindam
core  

Family's socioeconomic and demographic factors on elements of children's dental and oral health: A scoping review

Clinical and Experimental Dental Research, EarlyView.
Abstract Background Family plays a significant role in children's dental and oral health (DOH) elements, such as children's DOH knowledge and practice, the development of children's dental fear and anxiety (DFA), children's dental visits, and children's DOH status.
Wisnu Fadila, Mugia B. Rahardja, Puguh Prasetyoputra, Anne A. Suwargiani, Yanu E. Prasetyo, Eriska Riyanti   +5 more
wiley   +1 more source