Results 131 to 140 of about 6,660,576 (307)

Machine learning-based prediction of hernia risk in peritoneal dialysis patients: a comparative study of models and SHAP-driven interpretability analysis

Frontiers in Medicine
PurposeThis study aimed to predict the hernia risk in peritoneal dialysis patients using machine learning (ML) models and conduct an interpretability analysis.MethodsA total of 1,144 eligible PD patients (2010–2024) were divided into training (n = 800 ...
Yugang Cao, Xun Hu, Tao Fang, Jun Guo
doaj   +1 more source

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among US Veterans

Arthritis Care &Research, EarlyView.
Biomedical research involving US veterans continues to advance health care beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both veteran ...
Austin M. Wheeler, Joshua F. Baker, Jennifer L. Barton, Maria I. Danila, Tate M. Johnson, Kamini Kuchinad, Kaleb Michaud, Amir A. Razmjou, J. Steuart Richards, Namrata Singh, Isaac D. Smith, Katherine D. Wysham, Grant W. Cannon, Bryant R. England, Amy Joseph, Deana Lazaro, Katherine P. Liao, Courtney Loecker, Andreas Reimold, Beth I. Wallace, Ted R. Mikuls   +20 more
wiley   +1 more source

N-linked glycosylation sites with low occupancy support sustained circulation of the A(H3N2) influenza A virus in the human population

Journal of Virology
Glycosylation of the influenza A virus hemagglutinin is crucial for viral fitness and immune evasion. The hemagglutinin of contemporary human A(H3N2) influenza A viruses is extensively glycosylated with up to 13 putative glycosylation sites. Glycan types
Irina V. Alymova, Betlehem Mekonnen, Dongxia Wang, Ram P. Kamal, Wen-Pin Tzeng, Alexander S. Jureka, John R. Barr, Shane Gansebom, Ian A. York   +8 more
doaj   +1 more source

Real‐World Effectiveness and Safety of Secukinumab in Giant Cell Arteritis: An Italian Multicenter Cohort Study

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to evaluate the real‐world effectiveness and safety of secukinumab in patients with giant cell arteritis (GCA). Methods This multicenter retrospective study included patients with GCA who received secukinumab at 14 Italian centers with at least six months of follow‐up.
Luca Iorio, Federica Davanzo, Caterina Ricordi, Milena Bond, Ruggiero Mascolo, Jacopo Mora, Alessandro Tomelleri, Angelo Fassio, Francesca Cuzzocrea, Sara Monti, Edoardo Conticini, Fabiola Atzeni, Paolo Delvino, Carlotta Nannini, Augusta Ortolan, Francesco Pollastri, Ester Vivaldelli, Chiara Marvisi, Paola Toniati, Antonio Brucato, Alessandra Milanesi, Francesca Regola, Enrico Tombetti, Lorenzo Dagna, Roberta Ramonda, Christian Dejaco, Luca Quartuccio, Carlo Salvarani, Roberto Padoan   +28 more
wiley   +1 more source

Effect Modification of Cigarette Smoking on the Relationship Between Posttraumatic Stress Disorder, Other Mental Health Conditions, and Rheumatoid Arthritis Risk: A Large Case‐Control Study in US Veterans

Arthritis Care &Research, EarlyView.
Objective We examined associations of posttraumatic stress disorder (PTSD) and other mental health disorders (OMH) with rheumatoid arthritis (RA), accounting for effects of smoking. Methods We conducted a matched case‐control study, identifying incident RA cases and controls using national Veterans Health Administration data (2006–2019).
Kelsey Coziahr, Harlan Sayles, Tate M. Johnson, Joshua F. Baker, Punyasha Roul, Grant W. Cannon, Gary A. Kunkel, Katherine D. Wysham, Gail S. Kerr, Amir A. Razmjou, Isaac Smith, Jennifer L. Barton, Maria I. Danila, Jonathan S. Richards, Bryant R. England, Ted R. Mikuls   +15 more
wiley   +1 more source

Unsupervised Machine Learning Identifies Shared Biomechanical and Clinical Variation in Individuals with Knee Osteoarthritis and High Body Mass Index

Arthritis Care &Research, EarlyView.
Objective High body mass index (BMI ≥ 27 kg/m2) and aberrant gait biomechanics are primary risk factors for knee osteoarthritis (KOA), yet the specific loading patterns linked to clinical disease features remain unclear. Unsupervised machine learning (ML) was used to identify vertical ground reaction force (vGRF) waveform modes of variation and ...
Ashley N. Buck, J. Elyse Borgert, Hyeon Lee, Liubov Arbeeva, Yvonne M. Golightly, Richard F. Loeser, Leigh F. Callahan, Stephen P. Messier, Brian Pietrosimone, Amanda E. Nelson, James S. Marron   +10 more
wiley   +1 more source

Development of Patient‐Reported Outcome Measures for Early Systemic Sclerosis Across Disease Subtypes

Arthritis Care &Research, Accepted Article.
Objective Existing patient‐reported outcome (PRO) measures for systemic sclerosis (SSc) have important limitations, including inadequate coverage of early disease and limited inclusion of diffuse cutaneous (dcSSc) and limited cutaneous (lcSSc) subtypes.
George J. Greene, Chelsea Rose Perschon, Emilie Jaeger, Alain Lescoat, David Cella, Dinesh Khanna   +5 more
wiley   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

TOX-Related T-Cell Exhaustion as a Link Between Chronic Inflammation, Tumor Immunity, and Immunotherapy A Bibliometric and Mechanism-Oriented Review

Journal of Inflammation Research
Yun Cong, Ziwei Ma, Kai Zhong, Yaoqiang Bao, Shitao Lei, Pingping Qiao, Tuerganaili Aji, Yingmei ShaoHepatobiliary & Hydatid Disease Department, Digestive & Vascular Surgery Center, First Affiliated Hospital of Xinjiang Medical University, State ...
Cong Y, Ma Z, Zhong K, Bao Y, Lei S, Qiao P, Aji T, Shao Y   +7 more
doaj  

Clostridioides difficile infection in rifampin-sensitive pulmonary tuberculosis: a retrospective comparative study

Frontiers in Cellular and Infection Microbiology
BackgroundClostridioides difficile infection (CDI) is an important cause of hospital-acquired diarrhea but remains poorly characterized during tuberculosis treatment.
Yongheng Liu, Yongheng Liu, Cuizhu Ren, Cuizhu Ren, Yong Guo, Yong Guo, Adili Jumahan, Adili Jumahan, Tuersun Yueriyeti, Tuersun Yueriyeti, Jianzhong Yang, Jianzhong Yang, Chuanjian Shi, Chuanjian Shi   +13 more
doaj   +1 more source