Results 121 to 130 of about 205,176 (281)

Dams threaten salmonids by triggering temperature-dependent proliferative kidney disease

open access: yesCommunications Biology
Dams provide different services for human society, but they also significantly disrupt ecosystems by altering natural flow and temperature regimes. Here, we describe a novel, unappreciated threat posed by reservoirs to one of the world’s most popular ...
Magnus Lauringson   +5 more
doaj   +1 more source

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

open access: yesAdvanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin   +14 more
wiley   +1 more source

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

open access: yesAdvanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery   +10 more
wiley   +1 more source

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan   +12 more
wiley   +1 more source

Malaria transmission in the vicinity of impounded water: evidence from the Koka Reservoir, Ethiopia [PDF]

open access: yes
Malaria / Waterborne diseases / Disease vectors / Habitats / Disease control / Entomology / Epidemiology / Surveys / Dams / Reservoirs / Villages / Case studies / Africa / Ethiopia / Koka Reservoir / Rift Valley / Awash River ...
Jayasinghe, G.   +3 more
core  

Electro‐Stimulated Graphene‐Polymer Nanocomposites Enable Wearable Patches With Feedback‐Controlled Drug Release

open access: yesAdvanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Stimuli‐responsive nanomaterials capable of spatiotemporal control over drug release are of nanocomposite patch (“e‐Medi‐Patch”) engineered from biodegradable polycaprolactone (PCL), graphene nanoplatelets, and a redox‐active therapeutic, niclosamide. The hierarchical composite integrates π‐π interactions between aromatic drug molecules
Santosh K. Misra   +7 more
wiley   +1 more source

Porcine and Human Community Reservoirs of Enterococcus faecalis, Denmark

open access: yesEmerging Infectious Diseases, 2011
Jesper Larsen   +10 more
doaj   +1 more source

Ethological risk factors of West nile infection of wild birds in Senegal [PDF]

open access: yes, 2007
Serological studies performed in 2003, as well as viral isolations demonstrated that West Nile fever (WNF) was endemic in Senegal (West Africa). Large populations of potentially infected birds fly each year from West Africa to Europe.
Baillon, François   +7 more
core  

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Nosocomial infections: A problem of contemporary medicine [PDF]

open access: yesVojnosanitetski Pregled, 2005
Šuljagić Vesna   +1 more
doaj   +1 more source

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