Results 11 to 20 of about 206,799 (204)

Reservoir interactions and disease emergence [PDF]

Theoretical Population Biology, 2007
Animal populations act as reservoirs for emerging diseases. In order for transmission to be self-sustaining, a pathogen must have a basic reproduction number R0>1. Following a founding transmission event from an animal reservoir to humans, a pathogen has not yet adapted to its new environment and is likely to have an ...
Reluga, T., Meza, R., Walton, D. B., Galvani, A. P.   +3 more
openaire   +3 more sources

Experience with ustekinumab in reservoir Crohn's disease

Revista Española de Enfermedades Digestivas, 2021
Crohn's disease of the reservoir is a pathology of difficult diagnosis and complex approach due to the scarce documented evidence on it. Recently, studies have been published on the treatment strategies available for this entity. Based on the above, we have analyzed the experience of our center in the treatment of reservoir Crohn's disease with one of ...
Martínez Burgos, María, Angulo McGrath, Isabela, Amo Trillo, Víctor, Olmedo Martín, Raúl, Romero Caro, Patricia, Mostazo Torres, José, Jiménez Pérez, Miguel   +6 more
openaire   +3 more sources

The pathogenesis of zoonotic viral infections: Lessons learned by studying reservoir hosts

Frontiers in Microbiology, 2023
Zoonotic viral infections that cause severe disease or even death in some people may be asymptomatic or mild in reservoir hosts. Comparison of the pathogenesis of these two host categories may potentially explain the difference in disease.
Lineke Begeman, Debby van Riel, Marion P. G. Koopmans, Marion P. G. Koopmans, Thijs Kuiken   +4 more
doaj   +1 more source

Mycobacterium microti Infections in Free-Ranging Red Deer (Cervus elaphus)

Emerging Infectious Diseases, 2021
Infections with Mycobacterium microti, a member of the M. tuberculosis complex, have been increasingly reported in humans and in domestic and free-ranging wild animals.
Giovanni Ghielmetti, Anne M. Kupca, Matthias Hanczaruk, Ute Friedel, Hubert Weinberger, Sandra Revilla-Fernández, Erwin Hofer, Julia M. Riehm, Roger Stephan, Walter Glawischnig   +9 more
doaj   +1 more source

Rodent reservoirs of future zoonotic diseases [PDF]

Proceedings of the National Academy of Sciences, 2015
SignificanceForecasting reservoirs of zoonotic disease is a pressing public health priority. We apply machine learning to datasets describing the biological, ecological, and life history traits of rodents, which collectively carry a disproportionate number of zoonotic pathogens.
Barbara A, Han, John Paul, Schmidt, Sarah E, Bowden, John M, Drake   +3 more
openaire   +2 more sources

Native rodent species are unlikely sources of infection for Leishmania (Viannia) braziliensis along the Transoceanic Highway in Madre de Dios, Peru. [PDF]

, 2014
An estimated 2.3 million disability-adjusted life years are lost globally from leishmaniasis. In Peru's Amazon region, the department of Madre de Dios (MDD) rises above the rest of the country in terms of the annual incidence rates of human leishmaniasis.
Conrad, Patricia A, De Los Santos, Maxy, Ghersi, Bruno M, Lescano, Andres G, Mazet, Jonna AK, Montgomery, Joel M, Razuri, Hugo, Shender, Lisa A   +7 more
core   +9 more sources

Spatial and Temporal Distribution of Rodents during the Epizootic and Enzootic Periods of Plague, with a Focus on Exu, Northeastern Brazil

Tropical Medicine and Infectious Disease, 2021
The plague caused by the Yersinia pestis bacterium is primarily a flea-transmitted zoonosis of rodents that can also be conveyed to humans and other mammals.
Diego Leandro Reis da Silva Fernandes, Matheus Filgueira Bezerra, Bruna Mendes Duarte, Mayara Paes de França Silva, Hadassa de Almeida Souza, Elainne Christine de Souza Gomes, Alzira Maria Paiva de Almeida   +6 more
doaj   +1 more source

Susceptibility of Well-Differentiated Airway Epithelial Cell Cultures from Domestic and Wild Animals to Severe Acute Respiratory Syndrome Coronavirus 2

Emerging Infectious Diseases, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, and the number of worldwide cases continues to rise. The zoonotic origins of SARS-CoV-2 and its intermediate and potential spillback host reservoirs, besides humans, remain
Mitra Gultom, Matthias Licheri, Laura Laloli, Manon Wider, Marina Strässle, Philip V’kovski, Silvio Steiner, Annika Kratzel, Tran Thi Nhu Thao, Lukas Probst, Hanspeter Stalder, Jasmine Portmann, Melle Holwerda, Nadine Ebert, Nadine Stokar-Regenscheit, Corinne Gurtner, Patrik Zanolari, Horst Posthaus, Simone Schuller, Amanda Vicente-Santos, Andres Moreira-Soto, Eugenia Corrales-Aguilar, Nicolas Ruggli, Gergely Tekes, Veronika von Messling, Bevan Sawatsky, Volker Thiel, Ronald Dijkman   +27 more
doaj   +1 more source

Francisella tularensis in the United States

Emerging Infectious Diseases, 2005
The causative agent of tularemia, Francisella tularensis, is a formidable biologic agent that occurs naturally throughout North America. We examined genetic and spatial diversity patterns among 161 US F.
Jason Farlow, David M. Wagner, Meghan Dukerich, Miles Stanley, May Chu, Kristy Kubota, Jeannine Petersen, Paul Keim   +7 more
doaj   +1 more source

Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation [PDF]

, 2017
Current antiretroviral therapy (ART) for HIV/AIDS slows disease progression by reducing viral loads and increasing CD4 counts. Yet ART is not curative due to the persistence of CD4+ T-cell proviral reservoirs that chronically resupply active virus ...
Albert, Brice J, Barnes, Alexander B, Kyei, George B, Marshall, Garland R, Niu, Austin, Ramani, Rashmi, Ratner, Lee, Wender, Paul A, Williams, Robert M   +8 more
core   +2 more sources