Results 231 to 240 of about 205,476 (300)

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Influenza Pandemics After COVID-19: Still a Credible Threat in a Broader Pandemic Landscape. [PDF]

Infect Dis Clin Microbiol
Ergönül Ö, Akova M.
europepmc   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

The implementation gap: how Cuba's tuberculosis setback exposes a universal challenge for low-burden countries. [PDF]

Lancet Reg Health Am
Martínez-Rodríguez A, González-Díaz A, de Los Angeles León Venero M, García CP, Toledo Romaní ME.   +4 more
europepmc   +1 more source

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

A One Health Approach Reveals Farms as Hotspots for Co-Occurrence of <i>Mcr-1</i> and <i>bla</i> _NDM-1 Resistance Genes in Fuyang City, China. [PDF]

Infect Drug Resist
Meng Z, Bu Z, Guo H, Guo G, Gao X, Guo L, Li L, Zhang W.   +7 more
europepmc   +1 more source

Mechanistic Insights Into Photocatalytic Materials for Toxic Pollutants: Environmental Remediation of Personal Care Products

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Photocatalytic materials have emerged as promising solutions for environmental applications due to their ability to degrade organic pollutants under sunlight or artificial light. In this review, recent progress on the photocatalytic materials used for the degradation of pharmaceutical personal care products (PPCPs) in environmental ...
Urvashi Sen, Gunjan Chauhan, Surbhi Soni, Monika Vats, Anand Kumar, Indra Bahadur   +5 more
wiley   +1 more source

Genomic Surveillance of Epiphytic Pseudomonas syringae Highlights Shared Reservoirs and Cross-Habitat Threats to Cherry Orchards and Nearby Woodland Plants. [PDF]

Mol Plant Pathol
Zeng Z, Mansfield JW, Vadillo-Dieguez A, Connell J, Irvine J, Hulin MT, Frutos FD, Rabiey M, Grinberg NF, Harrison RJ, Xu X, Jackson RW.   +11 more
europepmc   +1 more source

Geometry Analysis of Two Photon Polymerized Microneedles—An Experimental and Simulated Approach

Journal of Applied Polymer Science, EarlyView.
This research investigates the mechanical stability of hollow, two‐photon‐polymerized microneedles for drug delivery. In an experimental setup, a steel stamp gradually compresses 1000 μm‐tall microneedles while recording their force–deformation response.
Cordelia F. Wittemann, Selina Burkert, Christos J. Karapatzakis, Alexander Schwegler, Andreas Heinrich   +4 more
wiley   +1 more source

Absence of hepatitis E virus in hedgehogs in northern Italy in 2022-2024. [PDF]

Virol J
Arnaboldi S, Benevenia R, Righi F, Scarazzato A, Lavazza A, Lelli D, Trogu T, Losio MN, Bertasi B.   +8 more
europepmc   +1 more source