Results 171 to 180 of about 1,832,821 (308)

The impact of temperature on canine Chagas disease transmission risk: A modeling study. [PDF]

PLoS Negl Trop Dis
Fiatsonu E, Mokhtar S, Ndeffo-Mbah ML.
europepmc   +1 more source

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Knowledge, attitudes, and practices toward zoonotic disease transmission among wildlife farmers in Vietnam. [PDF]

One Health Outlook
Nguyen HTT, Lindahl JF, Lâm S, Nguyen-Viet H, Dang-Xuan S, Unger F, Ling J, Lundkvist Å, Lee HS, Bett B.   +9 more
europepmc   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Isolation of toxigenic <i>Corynebacterium diphtheriae</i> from cutaneous lesions in a donkey in Ontario, Canada, 2024: Implications for zoonotic disease transmission and One Health approach. [PDF]

Can Commun Dis Rep
Okechukwu C, Rebellato S, Pitfield H, Magnusson K, Sereshk R, Slavic D, McClinchey H, Wilson S, Kus J, Lee C.   +9 more
europepmc   +1 more source

Transmission dynamics in infectious diseases

Mathematical Biosciences and Engineering, 2020
Gui-Quan Sun, Rui Xu
openaire   +4 more sources

Shellac‐Mediated Assembly of Nanoparticles for mRNA Delivery

Advanced Healthcare Materials, EarlyView.
A shellac‐mediated nanoparticle assembly strategy is presented, involving the complexation of mRNA and low‐molecular‐weight cationic molecules (e.g., polyethyleneimine, chitosan, lipids, and poly‐l‐lysine), followed by capping with shellac. This nanoparticle platform enables mRNA transfection following intravenous injection and facilitates gene editing
Meizhang Lu, Jingqu Chen, Zhixing Lin, Wanjun Xu, Tianzheng Wang, Shiyao Li, Die Yang, Frank Caruso   +7 more
wiley   +1 more source

Quantifying feral pig interactions to inform disease transmission networks. [PDF]

Elife
Proboste T, Turnlund A, Bengsen A, Gentle M, Wilson C, Harriott L, Fuller RA, Marshall D, Soares-Magalhaes RJ.   +8 more
europepmc   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Prison connectivity and disease transmission to neighboring communities: The role of prison staff. [PDF]

PNAS Nexus
Zhuo Y, Turney K, Sugie NF, Owens E, Chen MK.   +4 more
europepmc   +1 more source