Results 251 to 260 of about 22,218,716 (335)

Wnt/beta-catenin signaling: components, mechanisms, and diseases.

Developmental Cell, 2009
Bryan T. MacDonald, K. Tamai, Xi He
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Health impacts of extreme heat in medically at-risk populations: a space-time stratified case-crossover analysis in Belgium. [PDF]

BMC Public Health
Ali EA, Aerts R, Vaes B, Scheeren C, Beerten SG, Van de Vel K, Duarte E, Van Pottelbergh G.   +7 more
europepmc   +1 more source

Molecular mechanisms of stem cell therapy in alcoholic liver disease [PDF]

, 2014
Phillip Levine, Kelly McDaniel, Heather Francis, Lindsey Kennedy, Gianfranco Alpini, Fanyin Meng   +5 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Temporal Relationship Between Visceral Fat and Inflammation, and Their Joint Effect on Cardiometabolic Diseases: Evidence from the China Health and Retirement Longitudinal Study (CHARLS). [PDF]

J Inflamm Res
Lin M, Zhou Y, Wu R, Li S, Ni X, Xiao J, Han S, Tang H, Huang J, Wen J, Jiang L, Tan X, Chen Y.   +12 more
europepmc   +1 more source

Expression of Concern: Protective Role of Acetylsalicylic Acid in Experimental Trypanosoma cruzi Infection: Evidence of a 15-epi-Lipoxin A4-Mediated Effect.

PLoS Neglected Tropical Diseases
PLOS Neglected Tropical Diseases Editors
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

TeleAllergy: Potential of Telemedicine in Management of Patients With Allergies.

JMIR Hum Factors
Lindemann H, Hammer E, Bonifacio L, Greis C, Hartmann K.   +4 more
europepmc   +1 more source

Monocyte-to-HDL ratio (MHR) as a novel biomarker: reference ranges and associations with inflammatory diseases and disease-specific mortality. [PDF]

Lipids Health Dis
Arabi A, Abdelhamid A, Nasrallah D, Al-Haneedi Y, Assami D, Alsheikh R, Zughaier SM.   +6 more
europepmc   +1 more source