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Periodontal Disease and Cardiovascular Disease

Journal of Periodontology, 1996
It is our central hypothesis that periodontal diseases, which are chronic Gramnegative infections, represent a previously unrecognized risk factor for atherosclerosis and thromboembolic events. Previous studies have demonstrated an association between periodontal disease severity and risk of coronary heart disease and stroke.
Steven Offenbacher   +4 more
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Lyme disease

Current Opinion in Rheumatology, 1994
This chapter focuses on Lyme disease, a systemic illness caused by the spirochete Borrelia burgdorferi, considered the most common tick-borne disease in the United States. Since the original discovery of Lyme arthritis in the mid 1970s, the clinical spectrum of Lyme disease has been expanded to include a wide variety of organ systems, primarily the ...
openaire   +8 more sources

Refractory disease in autoimmune diseases

Autoimmunity Reviews, 2011
Refractory disease (RD) definition has different meanings but it is dynamic, according to knowledge and the availability of new drugs. It should be differentiated from severe disease and damage definitions and it must take into account duration of adequate therapy and compliance of the patient. It can be related to inadequate or inefficacious treatment
Cornelis Kallenberg   +2 more
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Kawasaki disease

Current Treatment Options in Cardiovascular Medicine, 2004
Kawasaki disease is an acute, self-limited vasculitis of childhood characterized by fever, bilateral nonexudative conjunctivitis, erythema of the lips and oral mucosa, changes in the extremities, rash, and cervical lymphadenopathy. Coronary artery aneurysms or ectasia develop in approximately 15 to 25% of untreated children with the disease and may ...
David Fulton, Jane W. Newburger
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Wilson’s Disease

Clinical Gastroenterology and Hepatology, 1998
Wilson's disease is an autosomal, recessive-inherited disorder of impaired biliary copper excretion that results in the accumulation of copper in various organs including the liver, the cornea and the brain. The Wilson's disease gene on chromosome 13 codes for a copper transporting P-type ATPase-ATP7B.
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Whipple's disease

Annals of the Rheumatic Diseases, 2002
Whipple's disease is a chronic systemic bacterial infection that predominantly affects middle-aged men. Antimicrobial therapy is curative. The causative agent has been identified as Tropheryma whippelii. A PCR-based diagnostic test is now available and is particularly useful in patients with early-stage or atypical disease.
openaire   +7 more sources

Is Alzheimer disease a disease?

Nature Reviews Neurology
Dementia, a prevalent condition among older individuals, has profound societal implications. Extensive research has resulted in no cure for what is perceived as the most common dementing illness: Alzheimer disease (AD). AD is defined by specific brain abnormalities - amyloid-β plaques and tau protein neurofibrillary tangles - that are proposed to ...
Amos D. Korczyn, Lea T. Grinberg
openaire   +2 more sources

Cardiovascular disease.

JAMA, 1989
The Thrombolysis in Myocardial Ischemia trial randomized patients with unstable angina or non-Q-wave myocardial infarction and found that thrombolytic therapy was not beneficial and may be harmful. Drug treatment of hypercholesterolemia improves survival in patients with established coronary artery disease.
J M, Gore, J E, Dalen
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Disease and Mental Disease

1973
One main outcome of Part I should be a realisation of the dependence of the derivative notions of mental health and mental disease upon the prior notions of (physical) health and (physical) disease. If this dependence were merely historical and etymological it would be of little present concern.
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Menière’s Disease or Ménière’s Disease or Meniere’s Disease?

Practica Oto-Rhino-Laryngologica, 2018
Tsutomu Nakashima   +2 more
openaire   +2 more sources

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