Results 51 to 60 of about 10,579,164 (312)

Antioxidant Effects of Rutin Trihydrate vs. Doxorubicin in Zebrafish Larvae: GSH, GPx, and GST Activity [PDF]

open access: yesE3S Web of Conferences
This study aimed to compare the clinical relevance of the novel drug rutin trihydrate with doxorubicin concerning their influence on the antioxidant enzymes GST, GPX, and GSH.
Seethalakshmi S., Praveen Kumar I.
doaj   +1 more source

Analysis of the human diseasome reveals phenotype modules across common, genetic, and infectious diseases [PDF]

open access: yes, 2014
Phenotypes are the observable characteristics of an organism arising from its response to the environment. Phenotypes associated with engineered and natural genetic variation are widely recorded using phenotype ontologies in model organisms, as are signs
Gkoutos, Georgios V   +2 more
core   +2 more sources

Is “chronic kidney disease” a disease? [PDF]

open access: yesJournal of Evaluation in Clinical Practice, 2018
AbstractSeveral philosophers of medicine have attempted to answer the question “what is disease?” In current clinical practice, an umbrella term “chronic kidney disease” (CKD) encompasses a wide range of kidney health states from commonly prevalent subclinical, asymptomatic disease to rare end‐stage renal disease requiring transplant or dialysis to ...
Smart, B, Stevens, R, Verbakel, J
openaire   +3 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Optimal treatment strategies for musculoskeletal diseases [PDF]

open access: yes, 2013
This paper presents a model which aims to find an optimal treatment time for patients with musculoskeletal diseases. The stochastic dynamic programming model presented is based on minimizing expected costs given a stochastic processes for cure with ...
Haugen, Kjetil K.
core   +1 more source

STILL'S DISEASE

open access: yesInternational Journal of Clinical Practice, 1969
George Frederic Still (1868‐1941) was one of 12 children, three of whom died in their first year of life and two later in childhood. He was brought up in Highbury, London. He obtained a scholarship to Merchant Taylor's School and then a further scholarship to Caius College, Cambridge, where he achieved a first class honours in the Classical Tripos.
openaire   +6 more sources

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

Pain in systemic connective tissue diseases [PDF]

open access: yes, 2015
Pain is frequent in patients with connective tissue diseases (CTDs), particularly those affected by systemic sclerosis (SSc) and systemic lupus erythematosus (SLE) in which it is virtually ubiquitous and can have different causes.
Atzeni, Fabiola   +4 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Surveillance and response systems for elimination of tropical diseases : summary of a thematic series in infectious diseases of poverty [PDF]

open access: yes, 2016
The peer-reviewed journal Infectious Diseases of Poverty provides a new platform to engage with, and disseminate in an open-access format, science outside traditional disciplinary boundaries.
Bergquist, Robert   +5 more
core   +3 more sources

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