Results 131 to 140 of about 2,696,673 (357)

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

An Ethical Overview on Cloning in Nigeria [PDF]

open access: yes, 2019
This work titled "An Ethical Overview on Cloning in Nigeria" analyzed the debate on cloning for which many scholars believe that cloning is not just ethically and morally acceptable, but beneficial in that they allow otherwise infertile couples to have ...
Ogar, Joseph Nkang
core  

Being Born Under Adverse Economic Conditions Leads to a Higher Cardiovascular Mortality Rate Later in Life: Evidence Based on Individuals Born at Different Stages of the Business Cycle [PDF]

open access: yes
We connect the recent medical and economic literatures on the long-run effects of early-life conditions, by analyzing the effects of economic conditions on the individual cardiovascular (CV) mortality rate later in life, using individual data records ...
Christensen, Kaare   +2 more
core   +3 more sources

Dysbiosis in inflammatory bowel diseases: egg, not chicken

open access: yesFrontiers in Medicine
There is agreement that inflammatory bowel diseases are, both in terms of species composition and function, associated with an altered intestinal microbiome.
Eduard F. Stange
doaj   +1 more source

Congenital Chagas's disease in an urban population: investigation of infected twins [PDF]

open access: green, 1978
Rodney Hoff   +4 more
openalex   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Gene Expression Profiling of Monozygotic Twins Affected by Psoriatic Arthritis

open access: yesOpen Access Rheumatology: Research and Reviews, 2021
Maria Maddalena Angioni,1 Alberto Floris,1 Ignazio Cangemi,1 Mattia Congia,1 Elisabetta Chessa,1 Sandro Orrù,2 Matteo Piga,1 Alberto Cauli1 1Rheumatology Unit, Department of Medical Sciences and Public Health, University of Cagliari, University ...
Angioni MM   +7 more
doaj  

Digital Twin Generators for Disease Modeling [PDF]

open access: yesarXiv
A patient's digital twin is a computational model that describes the evolution of their health over time. Digital twins have the potential to revolutionize medicine by enabling individual-level computer simulations of human health, which can be used to conduct more efficient clinical trials or to recommend personalized treatment options.
arxiv  

Digital Twin approach to Clinical DSS with Explainable AI [PDF]

open access: yesarXiv, 2019
We propose a digital twin approach to improve healthcare decision support systems with a combination of domain knowledge and data. Domain knowledge helps build decision thresholds that doctors can use to determine a risk or recommend a treatment or test based on the specific patient condition. However, these assessments tend to be highly subjective and
arxiv  

Central core disease in one of identical twins. [PDF]

open access: bronze, 1978
Michael E. Cohen   +2 more
openalex   +1 more source

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