Results 151 to 160 of about 2,696,673 (357)

Neurological impairment of the monozygotic twins with congenital infection presumed by Zika virus: Case report

open access: yesRevista Brasileira de Saúde Materno Infantil
Introduction: the increase in the incidence of congenital microcephaly in Brazil has been associated to the Zika virus outbreak. This case report aimed to describe the neurological impairment of monozygotic twins presumably due to an intrauterine ...
Ana Karina Rocha Hora Mendonça   +1 more
doaj   +1 more source

Current Progress of Digital Twin Construction Using Medical Imaging [PDF]

open access: yesarXiv
Medical imaging has played a pivotal role in advancing and refining digital twin technology, allowing for the development of highly personalized virtual models that represent human anatomy and physiological functions. A key component in constructing these digital twins is the integration of high-resolution imaging data, such as MRI, CT, PET, and ...
arxiv  

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

A multidisciplinary approach towards modeling of a virtual human lung

open access: yesnpj Systems Biology and Applications
Integrating biological data with in silico modeling offers the transformative potential to develop virtual human models, or “digital twins.” These models hold immense promise for deepening our understanding of diseases and uncovering new therapeutic ...
Timothy Lam   +4 more
doaj   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Chronic diseases and labor market outcomes in Egypt [PDF]

open access: yes
By causing a sizeable reduction in employment 6 percent and labor supply 19 percent, chronic diseases are responsible for a major efficiency loss in the Egyptian economy.
Fumagalli, Elena   +3 more
core  

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