Results 151 to 160 of about 45,703 (295)

Studies of twins: what can they tell us about the fetal origins of adult disease? [PDF]

, 2005
Ruth Morley, Terence Dwyer
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

The role of digital twins in P4 medicine: A paradigm for modern healthcare. [PDF]

NPJ Digit Med
Emmert-Streib F, Parkkila S, Laubenbacher R, Mannermaa A, Hood L, Yli-Harja O.   +5 more
europepmc   +1 more source

Case report of myometrial window following fetoscopic treatment of twin‐twin transfusion syndrome: indications of underlying collagen vascular disease? [PDF]

, 2017
Michael V. Zaretsky, David Manchester, Henry L. Galan, Nicholas Behrendt, Ahmed I. Marwan, Kenneth W. Liechty, Timothy M. Crombleholme   +6 more
openalex   +1 more source

α-Synuclein oligomers in skin biopsy of idiopathic and monozygotic twin patients with Parkinson’s disease [PDF]

, 2020
Samanta Mazzetti, Milo Jarno Basellini, Valentina Ferri, Erica Cassani, Emanuele Cereda, Matilde Paolini, Alessandra Maria Calogero, Carlotta Bolliri, Mara De Leonardis, Giorgio Sacilotto, Roberto Cilia, Graziella Cappelletti, Gianni Pezzoli   +12 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Technologies, Clinical Applications, and Implementation Barriers of Digital Twins in Precision Cardiology: Systematic Review. [PDF]

JMIR Cardio
Sarani Rad F, Bitaraf E, Jafarpour M, Li J.   +3 more
europepmc   +1 more source

A Genetic Study of Paget’s Disease (Osteitis Deformans) in Monozygotic Twin Brothers [PDF]

, 1952
Bertha M. Aschner, Lewis A. Hurst, L Roĭzin   +2 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Clinical Variability of ADPKD in Monozygotic Twins. [PDF]

Kidney Int Rep
Mohib O, Van Cauwelaert S, Pölsler L, Van Der Niepen P, Brussaard C, Van Vlem B, Schauer R, Harris PC, Janssens P.   +8 more
europepmc   +1 more source