Results 161 to 170 of about 2,696,673 (357)

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

A study of diabetes mellitus within a large sample of Australian twins. [PDF]

open access: yes, 2008
David L. Duffy   +9 more
core   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

Early Life Health and Adult Earnings: Evidence from a Large Sample of Siblings and Twins [PDF]

open access: yes
We study the relationship between early life health and adult earnings using a unique dataset that covers almost the entire population of Swedish males born between 1950 and 1970.
Lundborg, Petter   +2 more
core  

Digital Twins: How Far from Ideas to Twins? [PDF]

open access: yesarXiv
As a bridge from virtuality to reality, Digital Twin has increased in popularity since proposed. Ideas have been proposed theoretical and practical for digital twins. From theoretical perspective, digital twin is fusion of data mapping between modalities; from practical point of view, digital twin is scenario implementation based on the Internet of ...
arxiv  

Immune changes associated with insulin dependent diabetes may remit without causing the disease: a study in identical twins. [PDF]

open access: bronze, 1986
B. A. Millward   +8 more
openalex   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

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