129 GALLSTONE DISEASE IN SWEDISH TWINS IS LINKED TO ABCG8 D19H RISK GENOTYPE
Despina Katsika +6 more
openalex +1 more source
Birth Order, Sibship Size, and Housing Density in Relation to Tooth Loss and Periodontal Disease: A Cohort Study among Swedish Twins [PDF]
Lorelei A. Mucci
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A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
AI, digital twins, and healthcare utilization behaviour: evidence from a Swiss population survey. [PDF]
Witt CM, An J, Christen M.
europepmc +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Epilepsy concordance in monozygotic twins: the role of common genetic variants. [PDF]
Dang YL +5 more
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Extending the Reach of Immunogenic Cell Death-Related Signatures: Integrating Digital Twins into Precision Immunotherapy. [PDF]
Belančić A, Likić R.
europepmc +1 more source
P1-465 Education and cardiovascular disease incidence in Danish men and women. A discordant twin pair design [PDF]
Matias Vested +5 more
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