Results 221 to 230 of about 2,696,673 (357)

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Exploring the Potential of Digital Twins in Cancer Treatment: A Narrative Review of Reviews. [PDF]

J Clin Med
Giansanti D, Morelli S.
europepmc   +1 more source

Twin studies of Alzheimer's disease: An approach to etiology and prevention

, 1990
John C.S. Breitner, E. A. Murphy, Marshal F. Folstein, Kathryn Magruder-Habib   +3 more
openalex   +1 more source

The Occurrence of Chronic Disease and Other Conditions in a Large Population-based Cohort of Native Californian Twins [PDF]

, 2002
Myles Cockburn, Ann S. Hamilton, John Zadnick, Wendy Cozen, Thomas M. Mack   +4 more
openalex   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

The Georgia Cardiovascular Twin Study: Influence of Genetic Predisposition and Chronic Stress on Risk for Cardiovascular Disease and Type 2 Diabetes [PDF]

, 2006
Dongliang Ge, Yanbin Dong, Xiaoling Wang, Frank A. Treiber, Harold Snieder   +4 more
openalex   +2 more sources

The Swedish Young Male Twins Register: A Resource for Studying Risk Factors for Cardiovascular Disease and Insulin Resistance [PDF]

, 2002
Finn Rasmussen, Malin Johansson‐Kark
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Plasma N-Glycoproteomics in monozygotic twin pairs discordant for body mass index reveals an obesity signature related to inflammation and iron metabolism. [PDF]

Biol Direct
Muniandy M, Joenväärä S, van der Kolk BW, Tohmola T, Haltia H, Saari S, Hakkarainen A, Lundbom J, Kuula J, Groop PH, Kaprio J, Heinonen S, Renkonen R, Pietiläinen KH.   +13 more
europepmc   +1 more source

Hyperthyroid Graves' Disease and Primary Hypothyroidism Caused by TSH Receptor Antibodies in Monozygotic Twins: Case Reports.

, 1998
Junichi Tani, Katsumi Yoshida, Hiroshi Fukazawa, YOSHINORI KISO, NORIYO SAYAMA, Kouki Mori, YOSHIHIKO AIZAWA, HIRUNOBU HORI, NAOKI NAKASATO, Keishi Abe   +9 more
openalex   +2 more sources