Results 221 to 230 of about 47,212 (310)

Characteristics and functions of the gut microbiome in monozygotic twins with autism spectrum disorders of varying severity. [PDF]

World J Psychiatry
Huang YY, Li CY, Li Y, Fang H, Ke XY.
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Placental Abruption, Preterm Delivery, and Cardiovascular Disease in Twin Offspring. [PDF]

J Am Heart Assoc
Lee R, Rosenfeld EB, Valeri L, Kostis WJ, Ananth CV.   +4 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Discordant imaging findings in dizygotic twins with known exposure to maternal ZIKV infection during initial stages of pregnancy. [PDF]

IDCases
Adami-Teppa F, Marquez M, Escalona-Rodriguez MA, Blohm GM, Ascanio LC, Sordillo E, Lednikcy JA, Paniz-Mondolfi AE.   +7 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

A Twin Study on the Relation Between Positive Mental Health and Biological Aging. [PDF]

Int J Mol Sci
Fagnani C, Picardi A, Medda E, Salemi M, D'Ippolito C, Siniscalchi E, Salani F, Varalda GM, Marcon F.   +8 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Digital-Intelligent Precision Health Management: An Integrative Framework for Chronic Disease Prevention and Control. [PDF]

Biomedicines
Ma Y, Chen D, Xie J.
europepmc   +1 more source