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Twins With Alzheimer's Disease
Archives of Neurology, 1981Twins of identical appearance were both affected by Alzheimer's senile dementia. In one, dementia began in her late 60s. She died at age 74. In the other, onset was at age 83. She died of ovarian carcinoma at age 85. The histopathologic findings of Alzheimer's disease were confirmed in both twin sisters.
Robert H. Cook +2 more
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Archives of Neurology, 1981
To the Editor.— We read with interest the article by Cook et al (Archives1981;38:300-301) describing the occurrence of Alzheimer's disease (AD) in elderly twin sisters who appeared to be identical. In 1979, Sharman et al 1 first reported the occurrence of histologically confirmed AD in apparently identical 38-year-old male twins whose mother had died ...
Kenneth S. Kosik, Dennis J. Selkoe
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To the Editor.— We read with interest the article by Cook et al (Archives1981;38:300-301) describing the occurrence of Alzheimer's disease (AD) in elderly twin sisters who appeared to be identical. In 1979, Sharman et al 1 first reported the occurrence of histologically confirmed AD in apparently identical 38-year-old male twins whose mother had died ...
Kenneth S. Kosik, Dennis J. Selkoe
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Parkinson's disease in monozygotic twins
Annals of Neurology, 1986AbstractRecent studies of twins have demonstrated an unexpectedly low concordance of Parkinson's disease in monozygotic twins. Only two monozygotic twin pairs concordant for it have been reported. However, both pairs were atypical because of an early age at onset and other unusual features.
Joseph Jankovic, Avi Reches
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Archives of Dermatology, 1974
Eighteen pairs of twins who were registered in the Twin Registry files of the National Research Council with the diagnoses of psoriasis or atopic dermatitis were questioned and examined. Of these pairs, ten had psoriasis, four had atopic dermatitis, and four were found to have neither of the foregoing, but to have other skin diseases.
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Eighteen pairs of twins who were registered in the Twin Registry files of the National Research Council with the diagnoses of psoriasis or atopic dermatitis were questioned and examined. Of these pairs, ten had psoriasis, four had atopic dermatitis, and four were found to have neither of the foregoing, but to have other skin diseases.
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Alzheimer's disease in Finnish twins
The Lancet, 1996The genetics of Alzheimer's disease (AD) are obscure. Although most cases are sporadic half the patients with sporadic AD have a positive family history. The mode of genetic transmission and the role of environmental factors are unknown. The purpose of this study was to examine the contribution of genetic factors to the pathogenesis of AD in a twin ...
T Rajala +4 more
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Monozygotic twins with Parkinson's disease
Annals of Neurology, 1986AbstractA pair of monozygotic twins concordant for Parkinson's disease are described. The issue of genetic factors in Parkinson's disease is discussed.
W. C. Koller +4 more
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GAUCHER'S DISEASE IN IDENTICAL TWINS
Annals of Internal Medicine, 1958Excerpt Gaucher's disease is a rare familial disorder characterized by a disturbance of cerebroside metabolism with abnormal storage or retention of kerasin in the cells of the reticuloendothelial ...
Richard I. Crone, James J. Bergin
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International Journal of Dermatology, 1984
A 27‐year‐old, unmarried twin woman of the ethnic Malay presented with numerous tiny, firm, rough‐textured papules distributed symetrically over the faceb, neck, and chest for 13 years (Figs. 1 and 2) A few areas were covered with yellowish crusts and were slightly malodorous.
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A 27‐year‐old, unmarried twin woman of the ethnic Malay presented with numerous tiny, firm, rough‐textured papules distributed symetrically over the faceb, neck, and chest for 13 years (Figs. 1 and 2) A few areas were covered with yellowish crusts and were slightly malodorous.
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Concordant Disease in Identical Twins
JAMA, 1964A unique pair of identical twins were concordant for breast cancer, diabetes mellitus, nontoxic goiter, hypertension, cholecystitis, obesity, relaxed pelvic outlet, and myomata uteri. The medical literature for concordant breast cancer in identical twins is reviewed and there seems to be a strong tendency for these tumors to occur in the same breast ...
Edward F. Lewison, William D. Heizer
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Castleman's disease in identical twins
Virchows Archiv A Pathological Anatomy and Histology, 1982The authors present the first published case of angiofollicular lymph-node hyperplasia, observed in identical twins. In both cases the lesion had the same location, but there was a difference of two years in the time of presentation. A morphological description and discussion of pathogenesis are given.
F. García +5 more
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