Results 131 to 140 of about 5,052 (241)
Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon +5 more
wiley +1 more source
Association of nutrient supplement use in older adults with chronic diseases: a cross-sectional study. [PDF]
Tian H, Chen J.
europepmc +1 more source
Molecular rotors are fluorescent molecules that are sensitive to viscosity and temperature variations in the environment. They exhibit a direct correlation between fluorescence and viscosity within Newtonian fluids. However, this correlation becomes less straightforward in complex systems.
Flavia Di Scala +6 more
wiley +1 more source
Lower birth rate, greater female dementia risk: global and regional patterns and public health implications. [PDF]
You W.
europepmc +1 more source
Non-communicable diseases (NCD), historically considered to be associated with affluent regions, now comprise the greatest burden of disease in nearly every region of the world. Cardiovascular disease (CVD) mortality is foremost among these with approximately 80% of CVD deaths occurring in the developing world. Disease burden comparisons are infrequent
openaire +1 more source
Co‐assembly of rationally designed glycosaminoglycan‐binding peptides with sulfated glycosaminoglycans yields supramolecular hydrogels with tunable mechanics and matrix‐mediated cytokine retention. The glycosaminoglycans thereby act as cofactors, driving a coil‐to‐β‐sheet transition that triggers gelation.
Shirel Veretnik +8 more
wiley +1 more source
Living in historically redlined neighborhoods and biological aging among older adults. [PDF]
Fisk CE +4 more
europepmc +1 more source
Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro +25 more
wiley +1 more source
Sense of coherence is associated with daily free sugar consumption and oral health-related quality of life in 15-year-old school children attending government schools in Kandy district, Sri Lanka: a cross-sectional analytical study. [PDF]
Ratnayake DL, Ekanayake L.
europepmc +1 more source
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source

