Results 161 to 170 of about 180,869,100 (247)

Large language model chatbot-based text-to-SQL application for database analyses in liver diseases and hepatology research. [PDF]

JAMIA Open
Far AT, Sun S, Jutras G, Wang MB, Burns S, Owens J, Galvez V, Somsouk M, Lai JC, Lai K, Ge J.   +10 more
europepmc   +1 more source

Human Pancreatic Cancer Organoids

Cell Proliferation, EarlyView.
This guideline establishes a comprehensive framework for the application of patient‐derived pancreatic cancer organoids. It outlines the stringent technical requirements and testing methods necessary to ensure high fidelity to the original tumor tissue, including morphological assessment, pathological biomarker expression (e.g., CK19, CK7), and genetic
Aina He, Xiaolin Lin, Xiaozhe Qian, Jiasheng Mu, Zhonghua Tao, Jin Gu, Yonggang Wang, Ting Han, Hongling Zhao, Yalong Wang, Jian Zhang, Zunqiang Zhou, Ligang Xing, Changchun Zhou, Dongyuan Zhu, Zengjun Liu, Gang Chen, Qinghe Zhou, Xiaoguang Wang, Shasha Zhao, Xiao Liu, Dongyan Cao, Bin Yu, Zebing Liu, Jiabei Wang, Gengming Niu, Guiying Wei, Maorong Chen, Weiping Wang, Xiaonan Kang, Junmei Zhou, Shuai Gong, Ying Xie, Jianming Zhang, Xianming Kong, Chunyan Dong, Yanmei Zou, Lina Tang, Aijin Ma, Hua Xiong, Xuemei Liu, Tongbiao Zhao, Jie Hao, Xiuying Xiao, Dongxi Xiang   +44 more
wiley   +1 more source

Editorial: The emerging role of large language model chatbots in gastroenterology and digestive endoscopy. [PDF]

Front Med (Lausanne)
Gravina AG, Pellegrino R, Zagari RM.
europepmc   +1 more source

Splenic Stiffness Measurement: A New Frontier in the Management of Pediatric Portal Hypertension

Portal Hypertension &Cirrhosis, EarlyView.
Samannay Das, Tamoghna Biswas
wiley   +1 more source

Cystic Fibrosis and Colorectal Cancer Risk: Reprogramming of the Intestinal Epithelial Niche and Cell‐State Plasticity in the CFTR Modulator Era

Cell Proliferation, EarlyView.
In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar, Ines Pankonien, Margarida Amaral, Chee Y. Ooi, Thierry Jardé, Shafagh A. Waters   +5 more
wiley   +1 more source

Outcomes Following Esophageal Hydraulic Dilation in Patients With Disorders of Esophagogastric Junction Outflow. [PDF]

Clin Gastroenterol Hepatol
Cuff C, Krause A, Forattini F, Low EE, Robles L, Yadlapati R.   +5 more
europepmc   +1 more source

Non‐Invasive Fibrosis Testing in Adults With Obesity and MASLD: A Systematic Review and Meta‐Analysis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Adults with obesity are at increased risk of metabolic dysfunction‐associated steatotic liver disease (MASLD)‐related fibrosis, but the diagnostic performance of non‐invasive tests (NITs) in this population remains uncertain. This meta‐analysis evaluated NITs for detecting significant (≥F2) and advanced (≥F3) fibrosis in adults with ...
Patricia M. Ortega, Lucas Sabatella, Pinelopi Manousou, Adriana Arregui, Ahmed R. Ahmed, Chioma Izzi‐Engbeaya   +5 more
wiley   +1 more source

Higher Cardiorespiratory Fitness Is Associated With a Lower Burden of Metabolic Syndrome Traits: A Cross‐Sectional Analysis of 39 197 UK Adults

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To investigate associations of cardiorespiratory fitness (CRF) with metabolic syndrome (MetS) trait count, MetS prevalence and individual MetS traits in a large population‐based cohort. Materials and Methods This cross‐sectional study analysed data for 39 197 adults from a UK‐based independent healthcare charity (mean ± SD: age, 45.8 ± 9 ...
Scott A. Willis, Annalena Phillipp, Kevin Deighton, Christopher Goodwin, Daniel J. Cuthbertson, Shelley E. Keating, Christopher J. A. Pugh, Jonathan G. Stine, Gaël Ennequin, Alexis Couret, David J. Stensel, Guruprasad P. Aithal, Thomas Yates, James A. King   +13 more
wiley   +1 more source

Nutrition, Digestive System, and Clinical Gastroenterology. [PDF]

Nutrients
Fonseca J.
europepmc   +1 more source

Proteomic Analysis of Serum Extracellular Vesicles Revealed Fibulin‐3 as a Novel Predictive Biomarker for Hepatocellular Carcinoma in Patients With Chronic Hepatitis B

Hepatology Research, EarlyView.
We carried out proteomic analysis of serum extracellular vesicles to identify biomarkers predictive of hepatocellular carcinoma (HCC) development in patients with chronic hepatitis B receiving nucleos(t)ide analog therapy. Candidate proteins identified through proteomic analysis were subsequently quantified in serum by ELISA.
Emi Sometani, Kazuhiro Murai, Hayato Hikita, Jihyun Sung, Satoshi Muraoka, Hidenori Toyoda, Satoshi Tanaka, Takayuki Miyake, Shinji Kuriki, Kenji Fukumoto, Satoshi Shigeno, Yuta Myojin, Kazuki Maesaka, Kumiko Shirai, Yuki Makino, Yuki Tahata, Yoshinobu Saito, Takahiro Kodama, Ryotaro Sakamori, Jun Adachi, Tomomi Yamada, Tetsuo Takehara   +21 more
wiley   +1 more source