Abstract Background Surgical fundoplication is the standard treatment for refractory gastroesophageal reflux disease (GERD) with large (≥3 cm) hiatal hernias; however, its invasiveness is problematic in older adults and high‐risk patients. Anti‐reflux mucosal intervention (ARMI) is a less invasive endoscopic alternative; however, patients with large ...
Masachika Saino +12 more
wiley +1 more source
Detection of high-grade dysplasia and adenocarcinoma in Barrett's esophagus using high-resolution virtual chromoendoscopy versus the Seattle protocol: the CONVERSE study. [PDF]
Queneherve L +27 more
europepmc +1 more source
ABSTRACT Objectives Studies of non‐anesthesiologist‐administered propofol (NAAP) during colorectal endoscopic submucosal dissection (ESD) are scarce, particularly in the elderly. We evaluated its feasibility across a broad age range and identified factors associated with sedation‐related adverse events.
Yumi Kishi +16 more
wiley +1 more source
Serum creatinine to cystatin C ratio and risk of incident digestive diseases in middle-aged and older adults: a prospective national cohort study. [PDF]
Lin J +6 more
europepmc +1 more source
Evaluation of Mutation Risk Using Patient‐Derived Organoids in Patients With Lynch Syndrome
ABSTRACT Lynch syndrome (LS) is a hereditary cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes, most notably associated with colorectal cancer. Although LS patients face high risk of CRC, risk can vary even among those with the same pathogenic MMR germline mutations. We suggest a functional assay platform for
Youmi Shin +10 more
wiley +1 more source
With Gratitude and Pride: Reflections From the Editors-in-Chief. [PDF]
Rustgi VK, Srinivasan S.
europepmc +1 more source
A prospective study of 150 outpatients with moderate‐to‐severe UC initiating treatment. IUS is performed at baseline, day‐2, ‐7, ‐90 and week 52 alongside clinical, biochemical, endoscopic, patient‐reported and exploratory multiomics assessments. The primary endpoint evaluates whether early change in BWT predicts treatment escalation within 3 and 12 ...
Sabrina Josefsen +6 more
wiley +1 more source
Automated Deep Learning Detection of Hepatic Steatosis on Noncontrast Computed Tomography Scans and Discrepancy With Scan Reports. [PDF]
Yardeni D +11 more
europepmc +1 more source
ABSTRACT Nutritional therapy is critical in managing inherited metabolic diseases (IMDs), and includes specialized diets and single nutritional therapy products (sNTPs) such as vitamins, cofactors, and amino acids. Many sNTPs function as medicines, but are regulated as food (e.g., food supplements), which can limit access, reimbursement, and consistent
Nina N. Stolwijk +39 more
wiley +1 more source
A Multidisciplinary, Digitally-Integrated Life-Cycle Management Model for Early Gastrointestinal Cancer: Enhancing Care Coordination and Continuity. [PDF]
Yuan R +6 more
europepmc +1 more source

