Results 111 to 120 of about 454,454 (320)

Exosome-mediated effects and applications in inflammatory diseases of the digestive system. [PDF]

Eur J Med Res, 2022
Wu X, Xu X, Xiang Y, Fan D, An Q, Yue G, Jin Z, Ding J, Hu Y, Du Q, Xu J, Xie R.   +11 more
europepmc   +1 more source

A Case of Novel Coronavirus Disease 19 in a Chronic Hemodialysis Patient Presenting with Gastroenteritis and Developing Severe Pulmonary Disease. [PDF]

, 2020
Novel coronavirus disease 2019 (COVID-19) is a highly infectious, rapidly spreading viral disease with an alarming case fatality rate up to 5%.
Amin, Alpesh N, Chang, Yongen, Cheng, Timmy T, Choi, Grace, Ferrey, Antoney J, Gohil, Shruti, Hanna, Ramy M, Hsieh, Lanny, Huang, Susan S, Ivaturi, Kaushik, Kalantar-Zadeh, Kamyar, Lau, Wei Ling, Lee, Richard A, Nguyen, Lawrence, Park, Elisa, Reddy, Uttam, Rhee, Connie M, Tantisattamo, Ekamol, Tonthat, Sam, Wang, Brian   +19 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Volatile organic compounds as potential biomarkers for the diagnosis of digestive diseases. A review [PDF]

Consilium Medicum
Diseases of the digestive system are very common among the population around the world. Diagnosis of the diseases of this group is expensive and often invasive, which greatly limits its accessibility to the population.
Vladimir I. Pilipenko
doaj   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

A Simple Microbiome in the European Common Cuttlefish, Sepia officinalis. [PDF]

, 2019
The European common cuttlefish, Sepia officinalis, is used extensively in biological and biomedical research, yet its microbiome remains poorly characterized.
Abbo, Lisa, Durand, Amber, Gilbert, Jack A, Gottel, Neil R, Hanlon, Roger T, Lutz, Holly L, Mark Welch, Jessica L, Ramírez-Puebla, S Tabita, Schlundt, Cathleen, Sjaarda, Alexandra K   +9 more
core   +1 more source

RÉSUMÉ OF THE LITERATURE ON INFANT FEEDING AND DISEASES OF THE DIGESTIVE SYSTEM, FROM JULY, 1912, TO MARCH, 1913 [PDF]

, 1913
Maurice Ostheimer
openalex   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source