Results 111 to 120 of about 3,127,273 (305)

Design of Expert System for Digestive Diseases Identification Using Naïve Bayes Methodology for iOS-Based Application

Inform: Jurnal Ilmiah Bidang Teknologi Informasi dan Komunikasi, 2020
Shown symptoms in digestive diseases might be similar, resulting in patient’s suspected diseases before and after diagnosis attempt might turn out to be different. This paper aims to build a design of an expert system for digestive disease identification
Dewi Salma Salsabila, Rinabi Tanamal
doaj   +1 more source

Role of gut microbiota in pathogenesis of selected chronic diseases [PDF]

, 2019
The human digestive system is colonized by a huge number of microorganisms, that are referred to collectively as the gut microbiota. The composition of intestinal microorganisms are shaped from an early life and undergoes constant changes depending on ...
Gosiewski, Tomasz, Krawczyk, Agnieszka, Salamon, Dominika   +2 more
core  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Mathematical Homogenization in the Modelling of Digestion in the Small Intestine [PDF]

arXiv, 2011
Digestion in the small intestine is the result of complex mechanical and biological phenomena which can be modelled at different scales. In a previous article, we introduced a system of ordinary differential equations for describing the transport and degradation-absorption processes during the digestion.
arxiv  

PF-12 Colectomy by Rectal- Pull Through Technique for Colonic Tumor in Eight Years Old Dog [PDF]

, 2018
Dogs are one of those independent carnivores. However, dogs are also susceptible to digestion disease. In addition to diarrhea, obstruction or constipation, diseases that can also interfere with the digestive system are tumors of the digestive tract ...
Alamsari, Osye, Dirgahariyawan, Tri Cahyo, Zaenab, Siti, Zulfiati, Eva   +3 more
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Design Patterns which Facilitate Message Digest Collision Attacks on Blockchains [PDF]

arXiv, 2018
Message digest algorithms are one of the underlying building blocks of blockchain platforms such as Ethereum. This paper analyses situations in which the message digest collision resistance property can be exploited by attackers. Two mitigations for possible attacks are described: longer message digest sizes make attacks more difficult; and, including ...
arxiv  

Global analysis of a simplified model of anaerobic digestion and a new result for the chemostat [PDF]

, 2019
A. Bornh\"oft, R. Hanke-Rauschenbach, and K. Sundmacher, [Nonlinear Dyn., 73 (2013), pp. 535-549] introduced a qualitative simplification to the ADM1 model for anaerobic digestion. We obtain global results for this model by first analyzing the limiting system, a model of single species growth in the chemostat in which the response function is non ...
arxiv   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

EGFR inhibition augments the therapeutic efficacy of the NAT10 inhibitor Remodelin in Colorectal cancer

Journal of Experimental & Clinical Cancer Research
Background Colorectal cancer (CRC) is the second leading cause of cancer-related death worldwide, and treatment options for advanced CRC are limited. The regulatory mechanisms of aberrant NAT10-mediated N4-acetylcytidine (ac4C) modifications in cancer ...
Yongbin Zheng, Dan Song, Ming Guo, Chenhong Wang, Mingzhen Ma, Gongcai Tao, Licui Liu, Xiaobo He, Fengyu Cao, Dan Luo, Qingchuan Zhao, Zhongyuan Xia, Yanxin An   +12 more
doaj   +1 more source