Results 131 to 140 of about 3,127,273 (305)

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

open access: yesFEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma   +3 more
wiley   +1 more source

Analisis Kebutuhan Pengembangan Media Virtual Reality Sistem Pencernaan untuk Meningkatkan Berpikir Kritis Kelas V SD [PDF]

open access: yes
Learning media is an important part as a means so that students can understand the material well. However, in reality, sometimes the media used is not appropriate, which has an impact on students' lack of attention, low learning outcomes and lack of ...
Abidin, Yunus, Oktarizka, Dhea Annisa
core   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

open access: yesFEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal   +3 more
wiley   +1 more source

Establishment and biological characterization of radioresistant colorectal cancer cell lines

open access: yesFEBS Open Bio, EarlyView.
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu   +10 more
wiley   +1 more source

Application of network pharmacology in traditional Chinese medicine for the treatment of digestive system diseases

open access: yesFrontiers in Pharmacology
With the general improvement in living standards in recent years, people’s living habits, including their dietary habits, have changed. More people around the world do not follow a healthy diet, leading to an increase in morbidity and even mortality due ...
Shihao Zheng   +22 more
doaj   +1 more source

Temporal Patterns of Multiple Long-Term Conditions in Individuals with Intellectual Disability Living in Wales: An Unsupervised Clustering Approach to Disease Trajectories [PDF]

open access: yesarXiv
Identifying and understanding the co-occurrence of multiple long-term conditions (MLTC) in individuals with intellectual disabilities (ID) is vital for effective healthcare management. These individuals often face earlier onset and higher prevalence of MLTCs, yet specific co-occurrence patterns remain unexplored.
arxiv  

Lossless Image Compression Algorithm for Wireless Capsule Endoscopy by Content-Based Classification of Image Blocks [PDF]

open access: yesarXiv, 2018
Recent advances in capsule endoscopy systems have introduced new methods and capabilities. The capsule endoscopy system, by observing the entire digestive tract, has significantly improved diagnosing gastrointestinal disorders and diseases. The system has challenges such as the need to enhance the quality of the transmitted images, low frame rates of ...
arxiv  

Relationship of cognitive decline with glucocerebrosidase activity and amyloid‐beta 42 in DLB and PD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Dementia with Lewy bodies (DLB) and Parkinson's disease (PD) share clinical, pathological, and genetic risk factors, including GBA1 and APOEε4 mutations. Biomarkers associated with the pathways of these mutations, such as glucocerebrosidase enzyme (GCase) activity and amyloid‐beta 42 (Aβ42) levels, may hold potential as predictive ...
Maria Camila Gonzalez   +15 more
wiley   +1 more source

Systematic approach to the development of methods of prevention of gastro-intestinal diseases in newborn calves

open access: yesАграрная наука Евро-Северо-Востока, 2017
The main condition for the prevention of diseases in calves in early postnatal period is the formation of an optimal immunological status of cows-mothers, provision of colostral immunity and colonization resistance of mucous membranes in newborn calves ...
O. A. Burova, A. A. Blokhin
doaj  

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