Results 181 to 190 of about 2,975,652 (321)

Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles

open access: yesAdvanced Science, EarlyView.
Macrophages play a critical role in several pathophysiological diseases by being involved in the activation of adaptive and innate immune responses. The repolarization of macrophages using gold nanoparticles functionalized with glycans for a more selective targeting toward a restorative phenotype leads to an amelioration of the events.
Jennifer Fernandez Alarcon   +25 more
wiley   +1 more source

Socioeconomic and demographic disparities in the impact of digestive diseases in the middle East and North Africa (MENA) region. [PDF]

open access: yesInt J Equity Health
Al Ta'ani O   +10 more
europepmc   +1 more source

Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study reveals that KMT5C activates DNA damage repair to inhibit STING‐IRF3 pathway, downstream type I IFN signaling and CCL5 secretion, leading to the downregulation of CD8+ T cell infiltration and function in NSCLC, ultimately facilitating tumor progression.
Yunfeng Yuan   +11 more
wiley   +1 more source

Safety of naltrexone in patients with cirrhosis

open access: yesJHEP Reports
Background & Aims: Treatment of alcohol use disorder (AUD) improves survival in patients with alcohol-related cirrhosis. However, medications for alcohol use disorder (MAUD) are underutilized in this population, partially due to concerns regarding ...
Rachel Thompson   +3 more
doaj  

Shrimp Virus Regulates ROS Dynamics via the Nrf2 Pathway to Facilitate Viral Replication

open access: yesAdvanced Science, EarlyView.
Viruses manipulate host ROS as a strategy to achieve successful infection. WSSV exploits Nrf2 pathway to maintain ROS homeostasis and establishes a positive feedback loop to facilitate WSSV replication. Wsv220 competitively binds to Keap1 to activate Nrf2. Nrf2 up‐regulates LvG6PDH to produce more NADPH and GSH to eliminate excessive ROS.
Honghui He   +6 more
wiley   +1 more source

SPECTREPlex: an automated, fast, high-resolution enabled approach for multiplexed cyclic imaging and tissue spatial analysis. [PDF]

open access: yesCommun Biol
Anderson MD   +6 more
europepmc   +1 more source

Aging related symptoms, disease and cancer in digestive system: A reference for better performance to health evaluation and promotion

open access: bronze, 2011
Yasuhiro Nishizaki   +7 more
openalex   +2 more sources

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