Results 181 to 190 of about 268,573 (327)

An Organ‐on‐Chip Platform for Strain‐Controlled, Tissue‐Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis

Advanced Healthcare Materials, EarlyView.
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi, Anastasiya Börsch, Paola Occhetta, Robert Ivanek, Martin Ehrbar, Lisa Krattiger, Philipp Oertle, Marko Loparic, Ivan Martin, Marco Rasponi, Andrea Barbero   +10 more
wiley   +1 more source

Correlation Analysis Between Physical-Chemical and Biological Conditions in the River and the Incidence of Diseases in the City of Piracicaba, Brazil. [PDF]

Toxics
Souza AO, Amorim DJ, Pinto E.
europepmc   +1 more source

Cholelithiasis - current knowledge about one of the most common diseases of the digestive system

, 2023
Gabriela Demidowicz, Nina Lasota, Natalia Trąbka, M. Younes, Klaudia Kowalczyk, Katarzyna Cichoń, Małgorzata Chyćko, Julia CZARNOTA, Wojciech WIŚNIEWSKI, Maciej Lambach   +9 more
openalex   +2 more sources

Engineering a Human‐Sized Common Bile Duct Prototype with Regenerative Potential: In Vitro Evaluation of Mechanics, Function, Degradation, and Immune Modulation

Advanced Healthcare Materials, EarlyView.
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua, Marianna Barbuto, Matteo Calligaris, Roberto Di Gesù, Duilio Pagano, Rosalia Busà, Salvatore Gruttadauria, Simone Dario Scilabra, Antonio D'Amore, Maria Giovanna Francipane   +9 more
wiley   +1 more source

Bidirectional Risk Association Between Hidradenitis Suppurativa and Inflammatory Bowel Disease. [PDF]

Acta Derm Venereol
Lönndahl L, Najeeb M, Killasli H, Emtestam L, Ludwig RJ, Curman P.   +5 more
europepmc   +1 more source

A Targeted Redox‐Active Dual‐Action Pt(IV)‐Mn(II) Prodrug Displays Enhanced In Vivo Anticancer Activity

Advanced Healthcare Materials, EarlyView.
A new oxaliplatin‐based Pt(IV) prodrug bearing a Mn(II) superoxide dismutase mimic is synthesized and studied, in vitro and in vivo, in the context of colorectal cancer. Encapsulation of this prodrug in an easy‐to‐implement PEGylated micelle formulation demonstrated the highest in vivo anticancer activity among all the tested conditions, supporting the
Alvaro Lopez‐Sanchez, Henri Chédotal, Ram Pravin Kumar Muthuramalingam, Marine Thomas, Jia Ning Nicolette Yau, Priya Ranjan Sahoo, Clotilde Policar, Frédéric Batteux, Kadda Medjoubi, Andrea Somogyi, Giulia Adriani, Carole Nicco, Romain Coriat, Giorgia Pastorin, Hélène C. Bertrand   +14 more
wiley   +1 more source

Book Review: Diseases of the Digestive System [PDF]

Proceedings of the Royal Society of Medicine, 1964
openaire   +2 more sources

Correlation analysis of negative psychology on nursing care of patients with gastrointestinal diseases: A cross-sectional analysis from NHANES. [PDF]

Medicine (Baltimore)
Qu X, Zhao L, Kang C.
europepmc   +1 more source

DNA Barcoding‐Enabled Tracking of Lipid Nanoparticles: Drug‐Loading‐Dependent Biodistribution and Tumor Microenvironment Targeting

Advanced Healthcare Materials, EarlyView.
In this study, lipid nanoparticles are tracked in vivo using DNA barcodes to determine how varying drug loadings affect their delivery behaviors in mice. A cost‐effective strategy is developed for simultaneously monitoring the biodistribution of a library of lipid nanoparticles (LNPs).
Letao Xu, Rui Chen, Xing Wang, Dawei Liu, Yun liu, Chun‐Xia Zhao   +5 more
wiley   +1 more source

Safety of naltrexone in patients with cirrhosis

JHEP Reports
Background & Aims: Treatment of alcohol use disorder (AUD) improves survival in patients with alcohol-related cirrhosis. However, medications for alcohol use disorder (MAUD) are underutilized in this population, partially due to concerns regarding ...
Rachel Thompson, Tamar Taddei, David Kaplan, Anahita Rabiee   +3 more
doaj