Results 181 to 190 of about 2,975,652 (321)
Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles
Macrophages play a critical role in several pathophysiological diseases by being involved in the activation of adaptive and innate immune responses. The repolarization of macrophages using gold nanoparticles functionalized with glycans for a more selective targeting toward a restorative phenotype leads to an amelioration of the events.
Jennifer Fernandez Alarcon+25 more
wiley +1 more source
Socioeconomic and demographic disparities in the impact of digestive diseases in the middle East and North Africa (MENA) region. [PDF]
Al Ta'ani O+10 more
europepmc +1 more source
Diagnostic value of confocal laser endoscopy in digestive system diseases
Ying-Qiu Huang
openalex +1 more source
Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy
This study reveals that KMT5C activates DNA damage repair to inhibit STING‐IRF3 pathway, downstream type I IFN signaling and CCL5 secretion, leading to the downregulation of CD8+ T cell infiltration and function in NSCLC, ultimately facilitating tumor progression.
Yunfeng Yuan+11 more
wiley +1 more source
Safety of naltrexone in patients with cirrhosis
Background & Aims: Treatment of alcohol use disorder (AUD) improves survival in patients with alcohol-related cirrhosis. However, medications for alcohol use disorder (MAUD) are underutilized in this population, partially due to concerns regarding ...
Rachel Thompson+3 more
doaj
3. Digestive System Diseases 2) Hepato-biliary-pancreatic Diseases
Masahiko Sunaga+2 more
openalex +2 more sources
Shrimp Virus Regulates ROS Dynamics via the Nrf2 Pathway to Facilitate Viral Replication
Viruses manipulate host ROS as a strategy to achieve successful infection. WSSV exploits Nrf2 pathway to maintain ROS homeostasis and establishes a positive feedback loop to facilitate WSSV replication. Wsv220 competitively binds to Keap1 to activate Nrf2. Nrf2 up‐regulates LvG6PDH to produce more NADPH and GSH to eliminate excessive ROS.
Honghui He+6 more
wiley +1 more source
SPECTREPlex: an automated, fast, high-resolution enabled approach for multiplexed cyclic imaging and tissue spatial analysis. [PDF]
Anderson MD+6 more
europepmc +1 more source