The therapeutic efficacy of lipid nanoparticle(LNP)‐based drugs depends on endosomal escape. However, few methods are available for quantifying the efficiency of endosomal escape in vivo. Herein, a novel method for quantifying the endosomal escape efficiency index using magnetic resonance imaging is introduced.
Somin Lee +5 more
wiley +1 more source
SNP rs7549881, near SGIP1 at 1p31.3, is significantly associated with digestive disorders and Parkinsonism in women. [PDF]
Lehrer S, Rheinstein P.
europepmc +1 more source
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao +2 more
wiley +1 more source
Advancements and trends in digestive system autotransplantation: a bibliometric and visualization analysis. [PDF]
Abulaiti A +5 more
europepmc +1 more source
Microphysiological Systems of Lymphatics and Immune Organs
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain +2 more
wiley +1 more source
Sex differences in dementia risk: considering underlying medical conditions. [PDF]
Rotstein A +3 more
europepmc +1 more source
Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli +6 more
wiley +1 more source
Analysis of mortality trends and projected burden of digestive system cancer in China: a nationwide longitudinal analysis (2006-2020) with mortality forecasts to 2045. [PDF]
Feng Y +5 more
europepmc +1 more source
Biodegradable Implantable Electronics with Wireless Technology for Real‐Time Clinical Applications
The article explores how bioresorbable implantable electronics merge wireless communication and power delivery with biodegradable materials to enable real‐time clinical applications. It highlights advances in materials, system design, and medical uses across neural, cardiovascular, digestive, immune, and drug‐delivery systems.
Myeongki Cho +4 more
wiley +1 more source
An anatomically designed duodenal stent with physiological drainage: effective endoscopic rescue in persistent perforation. [PDF]
Li SW +6 more
europepmc +1 more source

