Results 181 to 190 of about 118,543 (323)

From pituitary cells to prostate gland in health and disease: direct and indirect endocrine connections

André Sarmento‐Cabral, Antonio C. Fuentes-Fayos, Fernando Mata Ordóñez, Antonio J. León‐González, Antonio J. Martínez‐Fuentes, Manuel D. Gahete, Raúl M. Luque   +6 more
openalex   +1 more source

Gut Microbiota Modulates Obesity‐Associated Skeletal Deterioration Through Macrophage Aging and Grancalcin Secretion

Advanced Science, EarlyView.
Obese gut‐microbiota derived lipopolysaccharides (LPS) induce bone marrow macrophage senescence and GCA secretion via activating TLR4/NF‐κB/MAPKs pathway. Clinically, obese patients are associated with higher serum GCA levels. Mice with depletion of GCA gene show resistance to skeletal deterioration caused by obesity and LPS‐induced chronic ...
Min Huang, Mei Huang, Ling Liu, Fang Yang, Chen He, Yu‐Chen Sun, Yu‐Rui Jiao, Xiang Tang, Jing Hou, Kai‐Xuan Chen, Wen‐Zhen He, Jie Wei, Hui‐Ling Chen, Xia Li, Chao Zeng, Guang‐Hua Lei, Chang‐Jun Li   +16 more
wiley   +1 more source

Altering the Hydrogen Isotopic Composition of the Essential Nutrient Water as a Promising Tool for Therapy: Perspectives and Risks. [PDF]

Int J Mol Sci
Yaglova NV, Obernikhin SS, Timokhina EP, Tsomartova ES, Yaglov VV, Nazimova SV, Ivanova MY, Chereshneva EV, Lomanovskaya TA, Tsomartova DA.   +9 more
europepmc   +1 more source

Deciphering Cell Type Abundance in Proteomics Data Through Graph Neural Networks

Advanced Science, EarlyView.
GraphDEC constructs pseudo bulk reference data using a mixup strategy, then learns low dimensional representations via autoencoders to model intra and inter dataset relationships. These are processed through a multi view adaptive neighborhood aware GNN, integrating reference, target, and joint graphs.
Zhiming Dai, Yujie Song, Tuoshi Qi, Hongyu Zhang, Huiying Zhao, Zheng Wang, Yuedong Yang, Yuansong Zeng   +7 more
wiley   +1 more source

Hyperparathyroidism-Jaw Tumor Syndrome Associated to a CDC73 Gene Pathogenic VARIANT and a Nonossifying Desmoplastic Fibroma of the Mandible. [PDF]

Case Rep Endocrinol
Elena C, Andrea C, Di Giovanni F, Alessandra L, Mirella F, Antonella M.   +5 more
europepmc   +1 more source

Macrophage‐Mediated Transport of Insoluble Indirubin Induces Hepatic Injury During Intestinal Inflammation

Advanced Science, EarlyView.
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu, Jingchun Shi, Heung‐Lam Mok, Cheng Lyu, Junbang Chen, Chunhua Huang, Hongyan Qin, Chengyuan Lin, Hor‐Yue Tan, Zhaoxiang Bian   +9 more
wiley   +1 more source

Autoimmune Polyglandular Syndrome Type 2 Presentation with Alopecia Universalis, Hashimoto's Disease, and Addison's Disease. [PDF]

Int Med Case Rep J
Sales-Morales KD, Torres-Neme N, Barrera-Villanueva V, Martínez-Carreón A.   +3 more
europepmc   +1 more source

Assessment and treatment of patients with hypothyroidism [PDF]

, 2009
Carson, M. N.
core  

Perovskite‐Graphene Heterostructure Biosensor Integrated with Biotunable Nanoplasmonic Ternary Logic Gate for Ultrasensitive Cytokine Detection

Advanced Science, EarlyView.
This work proposes the first perovskite/graphene heterostructure‐based FET biosensor with uniquely biotunable ternary logic gating functionality for the detection of human IL6 cytokines. The biosensor integrates a lateral perovskite‐on‐graphene heterostructure phototransistor with a vertical bio‐nano‐photonic filter, achieving ultrahigh sensitivity ...
Jiaxing Sun, Lin Zhou, Zening Li, Guolin He, Hongju Mao, Jianlong Zhao, John A. Hunt, Xianfeng Chen   +7 more
wiley   +1 more source

Dynamic 4 dimensional contrast enhanced MRI for localization in primary hyperparathyroidism. [PDF]

Endocrine
Altintop SE, Cerit MN, Cindil E, Sendur HN, Barlas T, Yalcin MM, Altinova AE, Akturk M, Toruner FB, Karakoc MA, Cerit ET.   +10 more
europepmc   +1 more source