The clinical application of mitoxantrone hydrochloride tracing in endoscopic radical resection of thyroid carcinoma. [PDF]
Sci RepCheng X, Chen L, Zang H, Li Y.
europepmc +1 more source
Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy
Advanced Science, EarlyView.This study reveals that breast cancer creates a hyperglycemic pre‐metastatic niche in bone prior to colonization and amplifies glucose metabolism post‐metastasis. To target this mechanism, a biomimetic enzyme‐engineered nanoplatform that disrupts tumor glycolytic pathways, proposing a therapeutic strategy to inhibit breast cancer bone metastasis by ...
Jianxin Ye +13 more
wiley +1 more source
Clinical evaluation of determinations of free and serum protein bound triiodthyronine (dextran gel filtration) [PDF]
, 1965 Heinze, H. G. +3 more
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The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
Advanced Science, EarlyView.This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen +6 more
wiley +1 more source
Hormonal Implications of SARS-CoV-2: A Review of Endocrine Disruptions. [PDF]
Scientifica (Cairo)Yskak A +9 more
europepmc +1 more source
Advances in Medical Devices for Augmented Acupuncture Therapy
Advanced Science, EarlyView.Traditional acupuncture therapy faces several challenges in clinical applications, such as complex operation procedures and prolonged therapeutic periods. By incorporating physical stimulations and drug delivery technologies, engineered acupuncture needles (EANs) can enhance therapeutic efficacy, improve patient compliance, as well as mitigate ...
Ruisi Cai +7 more
wiley +1 more source
Establishment of multifrequency magnetic resonance elastography for adrenal gland imaging: feasibility and reproducibility for assessing stiffness and fluidity in the healthy adrenal gland. [PDF]
Quant Imaging Med SurgWebster A +6 more
europepmc +1 more source
BRD4 Signaling Maintains the Differentiated State of β Cells
Advanced Science, EarlyView.The comprehensive exploration revealed the critical role of BRD4 in β cells. BRD4 plays a fundamental role in maintaining β cell differentiation because both long‐term and acute BRD4 deficiency result in a reduction in insulin secretion and downregulation of differentiation markers.
Fuqiang Liu +22 more
wiley +1 more source
Multimodal Imaging Approach to MEN-1 Syndrome-Associated Tumors. [PDF]
Diagnostics (Basel)Carli A +5 more
europepmc +1 more source
Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice
Advanced Science, EarlyView.Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu +14 more
wiley +1 more source