Results 211 to 220 of about 124,189 (286)

New Concepts of Regeneration and Renewal of Adrenal Chromaffin Cells. [PDF]

Int J Mol Sci
Yaglova NV, Obernikhin SS, Nazimova SV, Yaglov VV, Timokhina EP, Tsomartova ES, Ivanova MY, Chereshneva EV, Lomanovskaya TA, Tsomartova DA.   +9 more
europepmc   +1 more source

Targeting Mast Cell Activation and MIF‐Mediated Remodelling Enhances Chemotherapy Response in Pancreatic Cancer

Advanced Science, EarlyView.
Neoadjuvant gemcitabine plus nab‐paclitaxel (AG) reprograms pancreatic ductal adenocarcinoma by shifting malignant cells toward a classical phenotype and remodeling the tumor microenvironment. Despite enhancing cytotoxic NKT cells, AG activates tumor‐associated mast cells (TAMCs) and inflammatory CAFs through MIF signaling.
Libo Wang, Guangcong Shen, Guanpeng Xie, Zekun Li, Xiaoqing Ma, Mengyu Li, Ziyun Liu, Yadi Wang, Zongjing Lv, Qingxiao Fang, Huihui Sun, Ningning Zhao, Chao Yang, Tianxing Zhou, Yongjie Xie, Jun Yu, Jihui Hao   +16 more
wiley   +1 more source

Bilateral adrenal adenomas with autonomous cortisol secretion from both glands and autonomous aldosterone secretion from the left adrenal: a case report. [PDF]

J Yeungnam Med Sci
Han JE, Yoo S, Lee SA, Koh G.
europepmc   +1 more source

Thermosensory TRPV Heterotetramers Drive Seasonal Polyphenism: Molecular Basis of CcIav/CcNan‐PKCα‐AKH/AKHR Signaling in Pear Psyllid Morph Transition

Advanced Science, EarlyView.
At 2 5 °C, thermal activation initiates: i) CcIav/CcNan heterotetramer assembly → Ca2⁺ influx; ii) CcPKCα phosphorylation → AKH signaling potentiation; iii) CcAKH1 binding to membrane‐localized CcAKHR → energy mobilization (lipid catabolism/glycogenolysis) and vitellogenin transport via follicular patency; iv) Oocyte maturation → summer‐form nymph ...
Jianying Li, Zhixian Zhang, Yilin Wang, Yue Yang, Jiarui Wang, Xueyi Ruan, Songdou Zhang   +6 more
wiley   +1 more source

Pregnancy and Dry Eye Syndrome: A Review for Clinical Practice. [PDF]

Int J Mol Sci
Jaruchowska M, Przybek-Skrzypecka J, Skrzypecki J.   +2 more
europepmc   +1 more source

Predicting MammaPrint Recurrence Risk from Breast Cancer Pathological Images Using a Weakly Supervised Transformer

Advanced Science, EarlyView.
This study presents CPMP, a weakly supervised transformer model that predicts MammaPrint recurrence risk directly from routine histopathological images of early‐stage HR+/HER2− breast cancer patients. CPMP enables spatial heatmap visualization, analysis of cellular‐level interaction patterns, and an in‐depth characterization of morphological phenotypes
Chaoyang Yan, Linwei Li, Xiaolong Qian, Yang Ou, Zhidong Huang, Zhihan Ruan, Wenting Xiang, Hong Liu, Jian Liu   +8 more
wiley   +1 more source

A case-control study on autoimmune polyendocrine syndromes in patients with systemic lupus erythematosus. [PDF]

Rheumatology (Oxford)
Piovani E, Gozzoli GI, Della Pina SEL, Barison C, Orlandi C, Gatta E, Tomasi C, Fredi M, Cappelli C, Franceschini F.   +9 more
europepmc   +1 more source

From pituitary cells to prostate gland in health and disease: direct and indirect endocrine connections

André Sarmento‐Cabral, Antonio C. Fuentes-Fayos, Fernando Mata Ordóñez, Antonio J. León‐González, Antonio J. Martínez‐Fuentes, Manuel D. Gahete, Raúl M. Luque   +6 more
openalex   +1 more source

CDK4/6 Inhibitor Priming Enhances PD‐1 Blockade via Sellhi Neutrophil‐Induced Stat5a+ Progenitor Exhausted CD8+ T Cell

Advanced Science, EarlyView.
Activated tumor‐intrinsic cyclin D1‐CDK4/6 signaling attenuates lymphocyte infiltration, and consequently, and immunotherapy resistance in HNSCC. It is discovered that brief CDK4/6i priming before anti‐PD‐1 results in enhanced durability of ICB response durability through Stat5a+ progenitor exhausted CD8+ T cells induced by IL15‐secreted Sell(hi ...
Yu Zhang, Bao Sun, Rong Zhou, Zizhen Gong, Yong Han, Wenjie Tao, Chaoji Shi, Wuchang Zhang, Laikui Liu, Zhiyuan Zhang, Jiang Li, Qi Zhu, Weiwen Zhu, Ziyue Gu   +13 more
wiley   +1 more source

Mathematical modeling of the interaction between endocrine systems and EEG signals. [PDF]

Front Endocrinol (Lausanne)
Liu W.
europepmc   +1 more source