Results 41 to 50 of about 185,052,600 (243)

Pediatric endocrine surgery development

open access: yesЭндокринная хирургия, 2017
Department of pediatric surgery at the Endocrinology Research Centre has been around for nearly two years. During operation, surgical treatment has received more than 500 patients with various endocrine disorders.
Ivan I. Dedov   +5 more
doaj   +1 more source

Search for Genetic Predictors of Adult Autoimmune Polyendocrine Syndrome in Monozygotic Twins

open access: yesClinical Medicine Insights: Endocrinology and Diabetes, 2021
Autoimmune polyendocrine syndromes (APS) are a heterogeneous group of diseases characterized by the presence of autoimmune dysfunction of 2 or more endocrine glands and other non-endocrine organs.
Marina Yuryevna Yukina   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

COVID-19 and the Endocrine System: A Comprehensive Review on the Theme [PDF]

open access: yes, 2021
Background and aim. The review aimed to summarize advances in the topic of endocrine diseases and coronavirus disease 2019 (COVID-19). Methods. Scientific and institutional websites and databases were searched and data were collected and organized, when ...
Martina Capobianco   +11 more
core   +1 more source

Immune checkpoint inhibitors in cancer therapy: The leading role of the endocrinologist

open access: yesRevista Colombiana de Endocrinología, Diabetes y Metabolismo, 2022
The endocrine, immune, and nervous systems have a close functional relation from the embryonic development until the end of life, nevertheless this important homeostasis can be altered by any stressors such as infections, autoimmune diseases, neoplasms ...
Roberta Modica   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

On The Innervation of Salivary Glands and Treatment of Dry Mouth - An Experimental and Clinical Study [PDF]

open access: yes, 2009
Detailed knowledge of the innervation of the parotid gland is essential in basic studies on various neuroglandular phenomena as well as in various types of orofacial surgery. The innervation is more complex than usually depicted in Textbooks.
Khosravani, Nina
core   +1 more source

Impact of COVID-19 on the endocrine system

open access: yesЛечащий Врач, 2023
. Coronavirus infection is a highly contagious disease caused by the SARS-CoV-2 virus. Its targets are any organ systems. Infection begins with the entry of SARS-CoV-2 into target cells. They have type II angiotensin-converting enzyme receptors. SARS-CoV-
D. N. Zadumina   +2 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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