Results 101 to 110 of about 85,964 (197)

Multi‐Omics Signatures of Organ Clocks in Biological Aging and Disease: A Conceptual Framework for Organ‐Specific Aging Clocks

Aging Cell, Volume 25, Issue 5, May 2026.
Organ‐specific aging clocks integrating genomics, epigenomics, transcriptomics, proteomics, and metabolomics offer a more accurate assessment of biological aging than single‐omics approaches. This review proposes a multi‐omics framework emphasizing tissue data, longitudinal study designs, and clinically meaningful training outcomes to advance the ...
Maria Vasileiou, Gabor Liposits, Bara Barakat, Nam P. Nguyen   +3 more
wiley   +1 more source

CALR/HIF‐1α Positive Feedback Loop Drives CALR Upregulation to Promote EMT‐Mediated Bladder Cancer Progression via ROS/AKT Axis

Cancer Science, Volume 117, Issue 5, Page 1286-1302, May 2026.
This study first found that the high expression of CALR is due to a novel positive feedback loop with HIF‐1α in the tumor microenvironment: CALR stabilizes HIF‐1α protein, while HIF‐1α transcriptionally upregulates CALR expression, thereby self‐sustaining its high expression levels in BLCA.
Xintao Tian, Yue Liu, Zhiyuan Mi, Ye Liang, Zhao Zhang, Xiaocheng Ma, Huiqing Jia, Yuxuan Cao, Zhijuan Liang, Shaonan Yang, Guofeng Ma, Haitao Niu   +11 more
wiley   +1 more source

Urology [PDF]

, 2017
УЧЕБНО-МЕТОДИЧЕСКИЕ ПОСОБИЯУРОЛОГИЯУРОЛОГИЧЕСКИЕ ...
Plotnikov, P. V., Zebentaev, A. A.
core  

Genomic Profiling in Localized Prostate Cancer: Associations With Biochemical Recurrence and Response to Salvage Radiotherapy

Cancer Science, Volume 117, Issue 5, Page 1469-1480, May 2026.
Early screening for somatic alterations in localized prostate cancer could help predict biochemical recurrence risk and optimize salvage therapy selection. ABSTRACT The clinical significance of comprehensive genomic profiling (CGP) has been established in metastatic castration‐resistant prostate cancer (PC).
Kenji Zennami, Tetsuya Takimoto, Takuhisa Nukaya, Makoto Sumitomo, Mayu Takeda, Eiji Sugihara, Hideyuki Saya, Ryoichi Shiroki   +7 more
wiley   +1 more source

Gleason Regrading After Prostatectomy—Results From the Irish Prostate Cancer Outcome Research (IPCOR) Situated in the International Context

International Journal of Urology, Volume 33, Issue 5, May 2026.
ABSTRACT Background Accurate Gleason grading is crucial for prostate cancer (PCa) treatment decisions; incorrect assessment can lead to under‐ or overtreatment; discordance between biopsy and radical prostatectomy (RP) grades is a marker of this inaccuracy.
Noa Gordon, Ayush Amish Patel, Wasfa Farooq, William Watson, David Galvin   +4 more
wiley   +1 more source

Infectious mononucleosis, other infections and prostate-specific antigen concentration as a marker of prostate involvement during infection [PDF]

, 2016
Aksoy, Alanen, Ascherio, Ayatollahi, Banez, Basch, Bergh, Berrington de Gonzalez, Borgermann, Bosch, Carter, Catalona, Chen, Elgamal, Fan, Fedewa, Grinstein, Hasui, Heidenreich, Joshi, Kadayifci, Kadayifci, Kilic, Krystyna, Kuller, Kutok, Lilja, Luzuriaga, Malavaud, Mandel, Moyer, Olsson, Oremek, Rickinson, Rubertone, Sfanos, Silverberg, Sindhwani, Smith, Stamey, Sutcliffe, Sutcliffe, Sutcliffe, Tchetgen, Whitaker, Whittemore, Wolf   +46 more
core   +2 more sources

Primary care physician practices in the diagnosis, treatment and management of men with chronic prostatitis/chronic pelvic pain syndrome. [PDF]

, 2009
To describe practice patterns of primary care physicians (PCPs) for the diagnosis, treatment and management of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), we surveyed 556 PCPs in Boston, Chicago, and Los Angeles (RR=52%).
Calhoun, EA, Clemens, JQ, Kusek, JW, Litwin, MS, Markossian, T, McNaughton-Collins, M, Walker-Corkery, E   +6 more
core  

Small cell bladder cancer: should we consider prophylactic cranial irradiation?

International Brazilian Journal of Urology
Purpose: To describe the clinical characteristics, treatment patterns, and outcomes in patients with small cell bladder cancer at our institution, including those who received prophylactic cranial irradiation (PCI) for the prevention of intracranial ...
Tara Nikonow Morgan, Robert M. Turner II, Julian Baptiste, Timothy D. Lyon, Jodi K. Maranchie, Ronald L. Hrebinko, Benjamin J. Davies, Jeffrey R. Gingrich, Bruce L. Jacobs   +8 more
doaj   +1 more source

Urinary polymerase chain reaction for diagnosis of urogenital tuberculosis [PDF]

, 2008
Introduction: The aim of this study was to evaluate diagnostic value of urinary polymerase chain reaction (PCR) in urogenital tuberculosis (UTB). Materials and Methods: In 33 patients with confirmed diagnosis of UTB by urine culture and/or acid-fast ...
Shahidi, Shahrzad., Shirani, Majid., Yazdani, Mohammad.   +2 more
core   +1 more source

Total PSA and free PSA in patients with severe liver dysfunction

Indian Journal of Urology, 2003
Objectives: To evaluate the effect of liver diseases in patients, on serum free prostate specific antigen (JPSA) levels, total prostate specific antigen (tPSA) levels and fPSA/tPSA ratios.
Rama Devi Mittal, Mahendra Kumar Singh, Charles Selvaraju, Gourdas Choudhuri   +3 more
doaj