Results 101 to 110 of about 81,077 (211)

Regulation of Immune Checkpoints: From Molecular Mechanisms to Clinical Therapies

MedComm, Volume 7, Issue 6, June 2026.
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by unleashing antitumor immunity. This review comprehensively examines the molecular mechanisms underlying key immune checkpoints—including PD‐1/PD‐L1, CTLA‐4, and TIM‐3—and their clinical applications.
Qintao Ge, Liu Yu, Jiahe Lu, Aihetaimujiang Anwaier, Xiyue Xiao, Yonghao Chen, Dingwei Ye, Hailiang Zhang, Wenhao Xu, Wenbin Dai   +9 more
wiley   +1 more source

Constructing A Core Competency Evaluation Index System for Incontinence Specialist Nurses: A Delphi Study

Nursing Open, Volume 13, Issue 6, June 2026.
ABSTRACT Objectives This study aims to construct a core competency evaluation index system for incontinence specialist nurses; clarify the core competency elements required for incontinence nursing work; and provide a theoretical foundation for a comprehensive, objective and scientific evaluation of incontinence specialist nurses. Design A Delphi study
Xiao Miao Tian, Yu Zhen Chen, Su Mei Xie, Han Mei Shao, Yan Yi Li, Jian Liu   +5 more
wiley   +1 more source

Examining urogenital cancers in Turkey within the diagnosis related grouping data warehouse [PDF]

, 2013
Ülkemizde pilot uygulamalarla başlayıp 2011 yılından itibaren Sağlık Bakanlığı hastanelerinde uygulanan Teşhisle İlişkili Gruplar (TİG) önemli bir veri havuzunun oluşmasını sağlayacaktır. Bu çalışmada, bir yıllık TİG verileri içinde üroloji alanına giren
Yiğit, Pakize, Güler, Hasan, Demir, Mehmet, Aydın, Sabahattin   +3 more
core  

Effects of Exercise on Cancer‐Related Cognitive Impairment: An Umbrella Review of Systematic Reviews and Meta‐Analysis

Psycho-Oncology, Volume 35, Issue 6, June 2026.
ABSTRACT Background Cancer‐related cognitive impairment (CRCI) is a common consequence of cancer and its treatments, with mild but significant deficits in memory, attention or executive function. These symptoms negatively affect survivors' quality of life, daily functioning, and return to work.
Francisco Gómez‐Almeida, Daniel González‐Devesa, Clara Gacparski, Cristina Nombela, Oscar L. Veiga   +4 more
wiley   +1 more source

ОПРЕДЕЛЕНИЕ УРОВНЯ НАСТОРОЖЕННОСТИ (INDEX SUSPICION) В ОТНОШЕНИИ МОЧЕПОЛОВОГО ТУБЕРКУЛЕЗА У СПЕЦИАЛИСТОВ РАЗЛИЧНОГО ПРОФИЛЯ

, 2017
Polymorphism of clinical manifestations and absence of pathognomic symptoms are typical of urogenital tuberculosis. Since anti-microbial agents are widely used (fluoruquinolones, amikacin, rifampicin), it is more difficult to verify the diagnosis by ...
Д. П. Холтобин, E. V. Kulchavenya, V. T. Khomyakov, Е. В. Брижатюк, С. Ю. Шевченко, E. V. Brizhatyuk, S. Yu. Shevchenko, Е. В. Кульчавеня, D. P. Kholtobin, В. Т. Хомяков   +9 more
core   +1 more source

Prognostic factors and treatment choice for stage IV, low-volume metastasis hormone-sensitive prostate cancer: cross-sectional study of real-world data

Therapeutic Advances in Urology
Background: Many metastatic prostate cancer prognostics have been suggested, but few are validated. Nodal metastasis burden and baseline biochemical characteristics are overlooked in the currently accepted stratifications for metastatic hormone-sensitive
Mohamed Ibrahim Elewaily, Marina Campione, Mona Ali Hassan, Shobana Anpalakhan, Naoko Atsumi, Benjamin Smalley, Anza Ashraf, Joanna Gale, Akash Maniam, Giuseppe Luigi Banna   +9 more
doaj   +1 more source

A Feasibility Study of the Repurposing of Prazosin to Improve Treatment Outcomes in Men Receiving Radiotherapy for Prostate Cancer (MiniRaP‐00)

The Prostate, Volume 86, Issue 8, Page 891-899, June 2026.
ABSTRACT Background Further work is needed to improve treatment outcomes for prostate cancer (PCa), with the repurposing of the α1‐adrenoreceptor antagonists presenting a potential solution. This feasibility clinical trial presents the first prospective data of the use of an α1‐adrenoreceptor antagonist in men undergoing radiotherapy for PCa.
Liam D. King, David Christie, Daniel Cehic, Wendy Dare, Russ Chess‐Williams, Donna Sellers, Catherine McDermott, Alexandra McCarthy, Shailendra Anoopkumar‐Dukie   +8 more
wiley   +1 more source

Retrospective analysis of urethral anastomosis with ancillary maneuvers and intraoperative biaxial defect measurements to achieve a tension free guidance system for redo PFUDD treatment

BMC Urology
Objectives Redo surgery for pelvic fracture urethral distraction defects (PFUDDs) is still a challenge. the long urethral defect makes it difficult while the high tension increase the recurrence rate.
Kaile Zhang, Meng Liu, Tiantian Wang, Qiang Fu   +3 more
doaj   +1 more source

Socioeconomic and Demographic Factors in Genetic Testing Utilization Among Advanced Prostate Cancer Patients

The Prostate, Volume 86, Issue 8, Page 941-948, June 2026.
ABSTRACT Purpose Germline genetic testing in patients with advanced prostate cancer (PCa) is underutilized and hypothesized to be impacted by socioeconomic and demographic factors. This single institution, retrospective study assessed the association of income and social vulnerability with genetic referrals and testing.
Alexandra T. Skowron, Karen Childers, Courtney M. Rose, Kyle C. McElyea, Avery K. Supernois, Yousuf Hussain, Mohammed Baseer, Sunita Ghosh, Clara Hwang   +8 more
wiley   +1 more source

Single-port plus one in pediatric robotic-assisted Lich-Gregoir ureteral reimplantation for vesicoureteral reflux, a comparative analysis with short-term outcomes

BMC Urology
Objective To observe the safety and short-term outcomes of a new way of laparoscopic trocar placement in pediatric robotic-assisted Lich-Gregoir ureteral reimplantation for vesicoureteral reflux. Methods The retrospective study included 32 patients under
Jianglong Chen, Yingquan Kang, Shan Lin, Shaohua He, Yufeng He, Xinru Xu, Huihuang Xu, Guangxu You, Di Xu   +8 more
doaj   +1 more source