Results 161 to 170 of about 138,331 (303)

Not Just Half a Doctor: Promoting Humanism During Stressful Times

open access: yes
Annals of the Child Neurology Society, EarlyView.
Nigel S. Bamford   +7 more
wiley   +1 more source

Real‐world efficacy and toxicity of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma according to IMDC risk criteria—A multi‐center retrospective analysis on behalf of the GUARDIANS group

open access: yesInternational Journal of Cancer, EarlyView.
What's New? The combination of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma has demonstrated durable response and tolerability in clinical trials. However, inclusion criteria for clinical studies are restrictive, and patients in the real‐world setting tend to have more comorbidities.
Hendrik Dinkel   +21 more
wiley   +1 more source

easynem: An R package for computing and visualizing soil nematode ecological indices

open access: yesiMetaOmics, EarlyView.
Easynem is a user‐friendly and flexible R package that streamlines the complex analysis of soil nematode communities for evaluating soil health. It offers an integrated workflow for data processing, calculation of dozens of ecological indices, and comprehensive visualization of results to generate meaningful ecological insights.
Kunguang Wang   +8 more
wiley   +1 more source

Sex differences in dementia risk: considering underlying medical conditions. [PDF]

open access: yesAlzheimers Res Ther
Rotstein A   +3 more
europepmc   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

open access: yesiNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu   +6 more
wiley   +1 more source

Mesenchymal Stem Cell‐Mediated Vascular Regeneration in Diabetic Foot Ulcers via the Notch Signaling Pathway

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This graphical abstract illustrates the experimental design and key findings of the study on the role of mesenchymal stem cells (MSCs) and Notch signaling in diabetic foot ulcer (DFU) healing. The study involved five groups of BALB/c mice: Control, Model, MSCs Treatment, MSCs + Notch Inhibition, and MSCs + Notch Activation.
Feifei Li   +6 more
wiley   +1 more source

Patient Characteristics and Clinical Outcomes of Acute Pyelonephritis Treated in Mayo Clinic's Hospital-at-Home Program. [PDF]

open access: yesOpen Forum Infect Dis
Gomez-Cabello CA   +11 more
europepmc   +1 more source

Klippel‐Trénaunay‐Weber Syndrome: Prenatal Diagnosis and Review of the Literature

open access: yesJournal of Clinical Ultrasound, Volume 53, Issue 3, Page 535-546, March/April 2025.
This meta‐analysis demonstrates the high diagnostic accuracy of SZ‐CEUS for differentiating between malignant and benign focal liver lesions, as well as for HCC from non‐HCC lesions. The study shows better performance for smaller lesions and those with a higher proportion of malignancy.
Giuliana Orlandi   +13 more
wiley   +1 more source

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