Results 21 to 30 of about 128,030 (218)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

The dynamics of morbidity and provision of urological resources in the Republic of Kazakhstan

Clinical Epidemiology and Global Health
Background: This study aims to analyze the prevalence of diseases of the genitourinary system in the Republic of Kazakhstan from 2015 to 2022. Methods: We used the information from the primary registration database of the incidence of diseases of the ...
Turar Kurmanbekov, Karlygash Toguzbaeva, Kenesh Dzhusupov, Aigul Tazhiyeva   +3 more
doaj   +1 more source

Association of elderly age and chronic illnesses: Role of gender as a risk factor

Journal of Family Medicine and Primary Care, 2020
Background and Aims: Chronic diseases are the leading cause of death as well as disability worldwide. There is a little information about the prevalence of these diseases among Saudi elderly population.
Bandar Alhumaidi Alharbi, Nazish Masud, Fahad Abdullah Alajlan, Nwaf Ibrahim Alkhanein, Fares Thamer Alzahrani, Zaid Majed Almajed, Reema Khalid Mohammed Alessa, Ali Ibrahim Al-Farhan   +7 more
doaj   +1 more source

Improvement of prevention of loss of working capacity and rehabilitation of patients with disability due to non-oncological urological diseases

Український Журнал Нефрології та Діалізу, 2023
Improvement of medical and social care, including for patients with disabilities due to diseases of the urinary system, is today a priority task for preserving and restoring the working capacity of the population of Ukraine, which is especially relevant
S. Pasyechnikov, N. Saidakova, M. Mitchenko, V. Driianska, G. Kononova   +4 more
doaj   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

Dynamic Changes in Serum Glial Fibrillary Acidic Protein Levels Predicts Early Neurological Deterioration After Intravenous Thrombolysis in Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Minor strokes may be associated with early neurological deterioration (END) and disabilities. The objective was to investigate the role of serum glial fibrillary acidic protein (GFAP) levels in predicting END. Methods Data originated from a multicenter cohort study conducted prospectively.
Jie Zhou, Yang Qu, Reziya Abuduxukuer, Peng Zhang, Ting Wang, Jian‐Hua Gao, De‐Wang Pan, Zhi‐Mei Yuan, Chun‐Ying Li, Li‐Ping Chen, Jin‐Hua Chen, Ji‐Liang Gu, An‐Ying Wang, Li‐Gang Jiang, Liang Liu, Yong‐Fei Jiang, Chun‐Fei Wang, Yan Jia, Hong Xin, Chun‐Li Jiang, Ying‐Bin Qi, Xue‐Feng Hu, Song Li, Hang Jin, Zhen‐Ni Guo, Yi Yang, on behalf of the Biomarkers of Brain Injury Investigator Study Group, Lijuan Wang, Ting Wang, Jianhua Gao, Dewang Pan, Zhimei Yuan, Chunying Li, Liping Chen, Jinhua Chen, Jiliang Gu, Anying Wang, Ligang Jiang, Liang Liu, Yongfei Jiang, Chunfei Wang, Yan Jia, Hong Xin, Chunli Jiang, Yingbin Qi, Xuefeng Hu   +45 more
wiley   +1 more source

Collagen-based materials in male genitourinary diseases and tissue regeneration

Collagen and Leather
Male genitourinary dysfunction causes serious physical or mental distress, such as infertility and psychological harm, which leads to impaired quality of life.
Fangyuan Li, XinHuang, Ruiying Wang, Yujing Li, Lukanxuan Wu, Xinyu Qiao, Yuchan Zhong, Guidong Gong, Wei Huang   +8 more
doaj   +1 more source

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

Arthritis Care &Research, EarlyView.
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram, Heřman Mann, Danielle Hammond, Onima Chowdhury, Sinisa Savic, Yohei Kirino, Carmelo Gurnari, Maël Heiblig, Thibault Comont, Arsène Mekinian, Mrinal M. Patnaik, Lachelle D. Weeks, Gary Ho, Adam Al‐Hakim, Scott Goldberg, Marcela A. Ferrada, Sophie Georgin‐Lavialle, Peter C. Grayson, Emma M. Groarke, Bhavisha Patel, Megan Sullivan, Sarah A. Buckley, Bryan G. Harder, Raman Garcha, David B. Beck, Matthew J. Koster   +25 more
wiley   +1 more source

The Development of Rheumatoid Arthritis–Specific Ambulatory Care–Sensitive Conditions: Results of a Consensus Process

Arthritis Care &Research, EarlyView.
Objective Ambulatory care–sensitive conditions (ACSCs) serve as indicators of access, quality, and performance of the health system. This study aimed to determine rheumatoid arthritis (RA)‐specific ACSCs for use in the evaluation of care system access and quality.
Kara Irwin, Candace H. Feldman, Claire E. H. Barber, Gabriel Fabreau, Jake Jennings, Scott Patten, Cheryl Barnabe, Inflammatory Arthritis‐Specific ACSC Consensus Process Working Group   +7 more
wiley   +1 more source

CHRONICKIDNEYDISEASE IN CHILDREN AND RENAL REPLACEMENT THERAPYIN UKRAINE

Український Журнал Нефрології та Діалізу, 2015
Classification of Chronic Kidney Disease and stages of Chronic Renal Failure in children were compared. There was presented adapted Schwartz formula for estimated Glomerular Filtration Rate.
I. V. Bagdasarova, S. P. Fomina
doaj   +1 more source