Results 281 to 290 of about 300,158 (341)

Comparative analysis of the characteristics and trends of adverse drug reaction reports from patients in Japan and the Japanese Adverse Drug Event Report database

British Journal of Clinical Pharmacology, EarlyView.
Aims Spontaneous reporting of adverse drug reactions (ADR) after a product has reached the market is essential for drug safety. This study analysed patient ADR reports and compared them with reports from the Japanese Adverse Drug Event Report (JADER) database to identify differences and trends.
Masami Tsuchiya, Ryohkan Funakoshi, Koichi Masuyama, Nariyasu Mano, Satoko Hori, Taku Obara   +5 more
wiley   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Prevalence of malnutrition and appropriateness of nutritional support in hospitalized patients: a GLIM-based study. [PDF]

Front Nutr
Deng LM, Liu SP, Long JF, Mo H, Liu M, Liu JY, Zhang YL, Xu DF, Yu HZ, Chen L, Cai H, Yang SB, Xiang M, Liu M, Sun Y, Xie ZJ, Zeng MM, Xie GX.   +17 more
europepmc   +1 more source

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Prevalence, Risk Factors, and Multimorbidity Patterns in Climacteric Women with Hypertension. [PDF]

Int J Environ Res Public Health
Costa JG, Amaral AL, Tavares JB, Oliveira AK, Cunha ACR, Silva JC, Puga GM.   +6 more
europepmc   +1 more source

Machine learning methods for predicting adverse drug events: A systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Predicting adverse drug events (ADEs) in outpatient settings is crucial for improving medication safety, identifying high‐risk patients and reducing health‐care costs. While traditional methods struggle with the complexity of health‐care data, machine learning (ML) models offer improved prediction capabilities; however, their effectiveness in ...
Niaz Chalabianloo, Fatemeh Ahmadi, Mohammad Ali Omrani, Sheikh S. Abdullah, Neda Rostamzadeh, Atefeh Jafari, Lujain Izzedin, Kamran Sedig, Flory T. Muanda   +8 more
wiley   +1 more source

Magnitude of musculoskeletal disorder and associated factors among patients with diabetes mellitus in Ethiopia: Systematic review and meta-analyses. [PDF]

J Public Health Res
Tassew WC, Ferede YA.
europepmc   +1 more source

Global assessment of pain care quality for musculoskeletal disorders: Insights from the quality of care index (QCI) from 1990 to 2021. [PDF]

PLoS One
Xia Z, Wang J, Wen X.
europepmc   +1 more source

Kinematic Assessment of the Physician's Body Position and Musculoskeletal Loads During Breast and Abdominal Ultrasound Examinations. [PDF]

J Clin Med
Winder M, Hankus M, Ciekalski M, Rosół I, Miller-Banaś A, Guzik-Kopyto A, Steinhof-Radwańska K, Michnik R.   +7 more
europepmc   +1 more source