Results 291 to 300 of about 1,195,331 (367)

Infectious diseases of the respiratory system

, 2007
openaire   +1 more source

MCT1‐mediated Lactate Shuttle to Mitochondria Governs Macrophage Polarization and Modulates Glucose Homeostasis by Affecting β Cells

Advanced Science, EarlyView.
This study demonstrates that the transport of lactate to the mitochondria is of critical importance in determining the functions of macrophages by altering mitochondrial respiration. In macrophages, this lactate transport mechanism regulates glucose homeostasis by influencing the functions of insulin‐secreting cells in the pancreatic islets.
Lingling Chen, Yijun Lin, Xinyu Zhu, Shixuan Zhuo, Zixuan Li, Cheng Guo, Xiaoyi Ye, Jinzhu Chen, Shuying Wang, Yan Chen   +9 more
wiley   +1 more source

The global burden of climate-sensitive diseases in Brazil: the national and subnational estimates and analysis, 1990-2017. [PDF]

Popul Health Metr
de Sousa TCM, Barcellos C, Barreto ML.
europepmc   +1 more source

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

Advanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji, Yongli Ye, Jiadi Sun, Lina Sheng, Jinyou Li, Jin Yang, Bing Wu, Yuting Wang, Xingxing Gao, Liang Luo, Jianfeng Ping, Yinzhi Zhang, Xiulan Sun   +12 more
wiley   +1 more source

Flexible and scalable participatory syndromic and virological surveillance for respiratory infections: Our experiences in The Netherlands. [PDF]

PLoS One
Smit T, Carstens G, Han W, Bulsink K, de Bakker J, Elahi M, van Gageldonk-Lafeber R, van den Hof S, Eggink D, van Hoek AJ.   +9 more
europepmc   +1 more source

Causal relationship between type 2 diabetes and common respiratory system diseases: a two-sample Mendelian randomization analysis

Jie Chen, Xiaofeng Zhang, Gengyun Sun
openalex   +1 more source

Maximizing Efficacy of Cancer Nanovaccines and Immune Cells Landscape in Responders and Non‐Responders to Immunotherapy

Advanced Science, EarlyView.
To maximize the efficacy of cancer vaccines, adjuvants, collection, lysis, purification, oxidation, loading sites, and sizes, etc., are investigated. The optimized cancer nanovaccines loading whole tumor antigens can cure all or most tumor‐bearing mice in multiple mouse cancer models.
Xiangxiang Xu, Lu Diao, Jin Wang, Ao Zhu, Xianlan Chen, Yan Zheng, Yuhan Liu, Kang Hu, Jiashan Zhu, Cheng Ding, Chang Li, Yunzhi Pan, Jun Zhao, Mi Liu   +13 more
wiley   +1 more source

Multicentre retrospective observational study for development and validation of MAC prognostic score model. [PDF]

Sci Rep
Takeda K, Takazono T, Ide S, Yoshida M, Iwanaga N, Hosogaya N, Tsukamoto Y, Irifune S, Suyama T, Mihara T, Kondo A, Kobayashi T, Fukuda Y, Sasaki E, Sawai T, Higashiyama Y, Hashiguchi K, Hanaka M, Ii T, Fukushima K, Komiya K, Miyazaki T, Yatera K, Izumikawa K, Furumoto A, Yanagihara K, Mukae H.   +26 more
europepmc   +1 more source

The functional state of the respiratory system of the patients with proximal spinal muscular atrophy 5q (SMA 5q): from the natural history of the disease to the era of pathogenetic therapy. Problems and expectations

Svetlana E. Rastegina, D. Vlodavets, Yu. L. Mizernitskiy   +2 more
openalex   +1 more source