Results 301 to 310 of about 1,195,331 (367)

A Mitochondria‐Targeted Nanozyme Platform for Multi‐Pathway Tumor Therapy via Ferroptosis and Cuproptosis Regulation

Advanced Science, EarlyView.
This work reports a mitochondria‐targeted nanozyme platform, MIL‐Cu1.8S‐TPP/FA, which induces potent cuproptosis via localized delivery of Cu1.8S nanodots to mitochondria. Surface‐anchoring these nanodots onto MIL‐88B metal‐organic frameworks enhances both passive and active tumor targeting.
Chenguang Liu, Lingxiao Guo, Yuying Cheng, Jingjie Gao, Hanling Pan, Jiayi Zhu, Danting Li, Liqing Jiao, Caiyun Fu   +8 more
wiley   +1 more source

Deep-learning-based 3D content-based image retrieval system on chest HRCT: Performance assessment for interstitial lung diseases and usual interstitial pneumonia. [PDF]

Eur J Radiol Open
Oosawa A, Kurosaki A, Miyamoto A, Hanada S, Nei Y, Nakahama H, Takahashi Y, Mitsumura T, Takaya H, Baba T, Iwasawa T, Hori M, Kido S, Ogura T, Tomiyama N, Kishi K, Tamaoka M.   +16 more
europepmc   +1 more source

APPLICATION OF REFLEXOTHERAPY ACCORDING TO THE “HEXAGRAM BALANCING” METHOD IN THE COMBINED REHABILITATION OF DISEASES OF THE RESPIRATORY SYSTEM WITH PSYCHOEMOTIONAL DISORDERS

Igor MARTSENIUK, N. Svyrydova, Taras GUSEV, Yaroslav SIBIRYAKIN, Gennadii CHUPRYNA, Vitaly SEREDA   +5 more
openalex   +2 more sources

Calcitonin Gene‐Related Peptide (CGRP)‐Expressing Neurons in the External Lateral Parabrachial Area Regulate Pain‐Induced Sleep Disturbances

Advanced Science, EarlyView.
Lynch et al., identified novel targets on the wake‐promoting pathways that can effectively treat pain‐induced sleep disturbances. The authors demonstrated that Calcitonin gene‐related peptide‐expressing neurons (CGRP) in the external lateral parabrachial nucleus (PBelCGRP) serve as the primary relay node for pain stimuli that cause sleep disruption ...
Nicole Lynch, Roberto De Luca, Richard L Spinieli, Enrico Rillosi, Renner C Thomas, Samuel Sailesh, Nishta Gangeddula, Janayna D Lima, Sathyajit S Bandaru, Elda Arrigoni, Agustin Melo‐Carrillo, Rami Burstein, Stephen Thankachan, Satvinder Kaur   +13 more
wiley   +1 more source

Particulate matter air pollution: effects on the respiratory system. [PDF]

J Clin Invest
Hamanaka RB, Mutlu GM.
europepmc   +1 more source

Research Progress on the Association Between Gut Microbiota and Respiratory System Diseases

Jing Liu, Ruilin Sun
openalex   +2 more sources

NSP7 Molecular Degrader Attenuates Coronaviral Infection Through the β‐TrCP1/FBXO5 Axis

Advanced Science, EarlyView.
Host E3 ligase FBXO5 as a key regulator that promotes K48‐linked ubiquitination and proteasomal degradation of SARS‐CoV‐2 NSP7, thereby suppressing viral replication. NSP7 ubiquitination is co‐regulated by β‐TrCP1 and TAF1. Small molecule BC24877 disrupts β‐TrCP1‐mediated degradation of FBXO5, stabilizing FBXO5 and enhancing NSP7 clearance ...
Yao Tong, Travis B. Lear, Ferhan Tuncer, John J. Villandre, Áine N. Boudreau, Bo Lin, Irene Alfaras, Jason R. Kennerdell, Daniel P. Camarco, Mads B. Larsen, Yun Hua, Yanwen Chen, Meigin E. Chandler, Ricardo Pineda, Simon M. Barratt‐Boyes, John W. Evankovich, Toren Finkel, Yuan Liu, Bill B. Chen   +18 more
wiley   +1 more source

Periodontal Pathobionts and Respiratory Diseases: Mechanisms of Interaction and Implications for Interdisciplinary Care. [PDF]

Biomedicines
Kim B, Han N.
europepmc   +1 more source

Initial Respiratory System Involvement in Juvenile Idiopathic Arthritis with Systemic Onset Is a Marker of Interstitial Lung Disease: The Results of Retrospective Cohort Study Analysis

Konstantin E. Belozerov, E.A. Isupova, Natalia M. Solomatina, E. Gaidar, Maria Kaneva, И. А. Чикова, Olga Kalashnikova, А. А. Кузнецова, D. O. Ivanov, Mikhail M. Kostik   +9 more
openalex   +1 more source