Results 71 to 80 of about 86,805 (349)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Polyhexamethylene guanidine phosphate induces epithelial-to-mesenchymal transition and cancer stem cell-like properties via Wnt/β-catenin signaling in human bronchial epithelial cells

Ecotoxicology and Environmental Safety
Inhalation exposure to polyhexamethylene guanidine phosphate (PHMG-p), a primary component of humidifier disinfectants, has been linked to interstitial lung disease and potential carcinogenic effects.
Gi Ho Lee, Seung Yeon Lee, Yong-Wook Baek, Jungyun Lim, Kyu Hyuck Chung, Hye Gwang Jeong   +5 more
doaj   +1 more source

Bactericidal and disinfective properties of disinfectant «GK-10»

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2018
The article presents the results of research on bactericidal properties of the new domestic disinfectant «GK-10», which is a transparent solution of light yellow color, without mechanical inclusions with a specific odor. It is well mixed with water.
O.L. Tishyn, R.V. Khomiak, G.T. Kopijchuk, M.M. Danko, S.A. Ponomariova   +4 more
doaj   +1 more source

Make your own disinfectant

, 2020
Using disinfectant to keep our surroundings virus-free and hygienic during this Covid-19 pandemic has become standard practice at home and the workplace.
Long, Chiau Ming *, Goh, Choon Fu
core  

Repeated disinfectant use in broiler houses and pig nursery units does not affect disinfectant and antibiotic susceptibility in Escherichia coli field isolates

BMC Veterinary Research, 2020
Disinfectants are frequently used in animal production to reduce or eliminate the load of infectious agents and parasites in buildings and equipment associated with the housing or transportation of animals.
H. Maertens, E. Coillie, Sam Millet, S. Weyenberg, N. Sleeckx, Evelyne Meyer, Johan Zoons, Jeroen Dewulf, K. D. Reu   +8 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Comprehensive analysis of adverse outcome pathway, potency, human exposure supports carcinogenicity of polyhexamethylene guanidine phosphate in lung cancer

Ecotoxicology and Environmental Safety
In this study, we investigated the potential mechanisms by which polyhexamethylene guanidine phosphate (PHMG-p), a known respiratory irritant, may contribute to lung cancer development.
Yong Joo Park, Ha Ryong Kim, Jun Woo Kim, Jong-Hyun Lee, Younghee Kim, Jungyun Lim, Yong-Wook Baek, Kyu Hyuck Chung   +7 more
doaj   +1 more source

Assessment of antibiotic- and disinfectant-resistant bacteria in hospital wastewater, south Ethiopia: a cross-sectional study

Journal of Infection in Developing Countries, 2015
Introduction: Large quantities of antimicrobials are used in hospitals for patient care and disinfection. Antibiotics are partially metabolized and residual quantities reach hospital wastewater, exposing bacteria to a wide range of biocides that could ...
Sintayehu Fekadu, Yared Merid, Hunachew Beyene, Wondu Teshome, Solomon Gebre-Selassie   +4 more
doaj   +1 more source

The intravenous use of commercial disinfectants in the treatment of Novel Coronavirus (COVID-19): Unconventional, but is there evidence against it?

Asian Journal of Medical Sciences, 2020
Background: On 24th April 2020, United States President Donald J. Trump suggested the use of commercial surface disinfectants to treat patients infected with COVID-19. In his speech, President Trump also proposed medical research be conducted.
Adarsh Shah , Edmund Leung
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source