Results 131 to 140 of about 273,619 (339)
Advanced Science, EarlyView.TRPA1+αCGRP+ sensory neurons in the nodose ganglion detect external insults such as lipopolysaccharide (LPS) and interact directly with pulmonary neuroendocrine cells (PNECs), promoting their activation and proliferation. This neural‐epithelial interaction amplifies lung inflammation.
Jie Chen +16 more
wiley +1 more source
Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development
Advanced Science, EarlyView.This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen +11 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng +15 more
wiley +1 more source
Epidemiological study concerning the characteristics of organic pig farming in selected European countries [PDF]
, 2011 Interviews and on-farm assessments were conducted in a total of 101 organic pig farms in different European countries (Austria, Denmark, France, Germany, Italy, and Sweden) to gain knowledge about farm management and health status of organic pigs in ...
Bochicchio, Davide +14 more
core
Advanced Science, EarlyView.Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu +13 more
wiley +1 more source
Progress in the application of new ultraviolet disinfection technology
Shanghai yufang yixueWith the pandemic of COVID-19, the World Health Organization warns that disease X is on the verge of a global outbreak, and the problem of multidrug-resistant bacterial infections in medical and healthcare institutions becomes more serious. Compared with
ZHU Renyi, ZHANG Yucheng, TIAN Liang
doaj +1 more source
Development of Teleoperated Robotic System for Remote Intraocular Microsurgery
Advanced Science, EarlyView.A teleoperated robotic system, characterized by micrometer‐scale precision and a remote center of motion design, is developed and validated to ensure the safety and flexibility of remote intraocular surgery. This system exhibits superior performance in experimental evaluations and holds significant potential for advancing remote microsurgery ...
Andi Xu +30 more
wiley +1 more source