Senescent synovial intimal fibroblasts (SIF) are identified as key drivers of osteoarthritis. They promote M1 macrophage polarization and cartilage degeneration via the ANGPTL4–α5β1 axis, regulated by transcription factors EGR1 and ATF3. Pharmacological inhibition of this pathway alleviates disease, revealing SIF senescence as a promising therapeutic ...
Muhai Deng +7 more
wiley +1 more source
Evaluating the Potential Inhibition of PP2A by Nodularin-R Disinfection By-Products: Effect and Mechanism. [PDF]
Li M, Fu C, Shi Q, Yang S, Zong W.
europepmc +1 more source
Optimizing disinfectant residual dosage in engineered water systems to minimize the overall health risks of opportunistic pathogens and disinfection by-products. [PDF]
Zhang C, Lu J.
europepmc +1 more source
Simultaneous removal of estrogens and pathogens from secondary treated wastewater by solar photocatalytic treatment [PDF]
Chatzisymeon, E. +4 more
core
This study explores a novel E‐tattoo made from PVBVA fibers coated with Ti3C2Tx MXene. The device is designed to harvest energy directly from the human body, providing power for itself. The research demonstrates the E‐tattoo's capability for charge storage and its potential for health monitoring through integrated ECG and EMG sensing, all within a ...
Ajay Pratap +16 more
wiley +1 more source
Nitrate and disinfection by-products in drinking water and risk of ovarian cancer. [PDF]
Ammons S +8 more
europepmc +1 more source
[Determination of 13 halobenzoquinone disinfection by-products in drinking water using solid phase extraction-ultra performance liquid chromatography-triple quadrupole mass spectrometry]. [PDF]
Wang YY, Li LL, Lü J, Chen YY, Zhang L.
europepmc +1 more source
Nanozymes for Energy and Environmental Sustainability
At present, the widely used nanozymes are oxidoreductase and hydrolase, which have proved to have great application prospects in energy and environment. ABSTRACT Nanozymes have shown remarkable promise in addressing pressing challenges in energy and environmental sustainability.
Xiaoqi Li, Jinxing Chen, Shaojun Dong
wiley +1 more source
Invited Perspective: Drinking Water Disinfection By-Products and Cancer-A Historical Perspective. [PDF]
Villanueva CM.
europepmc +1 more source
Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang +17 more
wiley +1 more source

