Results 51 to 60 of about 114,617 (297)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Postmagmatiс tectonics of granites and morphostructure the Northern Tien Shan

open access: yesЛитосфера, 2016
The granites are represented significant volumes (up to 50% or more) of the continental upper crust, and, certainly, they should influence on the formation of the crust structure and peculiarities of its evolution. Is generally assumed that after cooling
M. G. Leonov   +3 more
doaj   +2 more sources

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini   +28 more
wiley   +1 more source

Potential of ultrasound treatment for sludge reduction [PDF]

open access: yes, 2008
The potential of ultrasound treatment for sludge reduction during the activated sludge process was assessed. Batch and dynamic disintegration studies were completed using an activated sludge pilot-scale plant fed with settled sewage that was comprised ...
Minervini, Davide
core  

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

The Political Logic of Disintegration: Seven Lessons from the Soviet Collapse. CEPS Essay (No. 1), September 2012 [PDF]

open access: yes, 2012
In short, the European Union, as we know it, no longer exists. The very foundations on which it was built are eroding. Shared memories of the Second World War have faded away – half the 15- and 16-year-olds in German high schools do not know that Hitler ...
Krastev, Ivan
core  

Atomistic Theory of Ostwald Ripening and Disintegration of Supported Metal Particles under Reaction Conditions

open access: yes, 2013
Understanding Ostwald ripening and disintegration of supported metal particles under operating conditions has been of central importance in the study of sintering and dispersion of heterogeneous catalysts for long-term industrial implementation.
李微雪   +3 more
core   +1 more source

Populism as a Problem of Social Disintegration? A Comparative Analysis of the Socio-Integrational Underpinnings of Populism in Europe [PDF]

open access: yes, 2022
This project focuses on the explanation of populist attitudes with particular emphasis on the role of social (dis-)integration. Following recent research that breaks up the too rigid conceptualisation of economic and cultural drivers of populism, I ...
Filsinger, Maximilian
core  

Brexit and the United Kingdom-European Union relationship from the perspective of a complex adaptive system

open access: yesForo Internacional, 2022
The UK-EU relationship has been depicted as awkward, and Brexit represents the pinnacle of this strangeness. This paper uses the Complex Adaptive Systems framework and the Containers, Differences, Exchanges (CDE) model to understand Brexit as a turning ...
Angélica Saraiva Szucko
doaj   +1 more source

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