Results 71 to 80 of about 4,401 (143)

Intrinsic specificity of a ‘core’ TIP60 acetyltransferase complex in Drosophila

open access: yesThe FEBS Journal, Volume 293, Issue 11, Page 3259-3273, June 2026.
The intrinsic substrate selectivity of the Drosophila TIP60‐core acetyltransferase was determined using synthetic nucleosome arrays. Targeted mass spectrometry revealed site‐specific acetylation of histones H2A, H2A.V, and H4, uncovering distinct acetylation rates and patterns across individual lysines.
Silke Krause   +5 more
wiley   +1 more source

The NF‐κB Signalling Pathway: Mechanisms, Consequences and Therapeutic Targets

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Nuclear Factor‐kappa B (NF‐κB) is a master transcriptional regulator orchestrating critical cellular processes, predominantly immunity and inflammation. However, its aberrant constitutive activation has emerged as a unifying pathogenetic hallmark across diverse malignancies, autoimmune disorders, and chronic inflammatory diseases.
Bherouz Pourdad, Arash Pourdad
wiley   +1 more source

Task Performance and Queen Presence Influence the Brain Transcriptome in a Bumble Bee (Bombus terrestris) With a Flexible Division of Labour System

open access: yesMolecular Ecology, Volume 35, Issue 11, June 2026.
ABSTRACT Division of labour in reproduction and in task performance are two hallmarks of insect societies. Bumble bees and honey bees are both classified as eusocial, but differ in the social organization of their colonies and in the hormonal regulation of division of labour.
Hagai Yehoshua Shpigler   +8 more
wiley   +1 more source

The abundance of pollen coat small signaling proteins shows limited convergence between independent selfing transitions in Arabidopsis and Capsella

open access: yesNew Phytologist, Volume 250, Issue 5, Page 3460-3474, June 2026.
Summary In plants, a key example of convergence is the repeated evolution of floral traits associated with the transition from outcrossing to self‐fertilization, often resulting in the ‘selfing syndrome’ (e.g. reduced flower size and loss of scent). However, potentially overlooked changes concern the pollen coat, which plays a role in different aspects
Ömer İltaş   +7 more
wiley   +1 more source

Poplar miR1447 Is a Negative Regulator of Disease Resistance Through the SA‐Dependent Pathway

open access: yesPlant Biotechnology Journal, Volume 24, Issue 6, Page 3616-3633, June 2026.
ABSTRACT Although microRNA1447 (miR1447) regulates poplar responses to abiotic stress and pest infestation, how miR1447 regulates poplar immunity against pathogens and its underlying molecular mechanisms remain to be elucidated. Here, we revealed that miR1447 functioned as a negative regulator of poplar disease resistance against fungal and bacterial ...
Dandan Xiao   +11 more
wiley   +1 more source

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