Results 161 to 170 of about 18,420 (264)

Dismantling structural violence to enable structural transformation and consequently social inclusion. [PDF]

World Psychiatry
Jones N.
europepmc   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

A Dismantling Study of Comprehensive Cognitive Remediation for Improving Employment Outcomes: What is the Role of Computer Cognitive Training? - CORRIGENDUM. [PDF]

Psychol Med
McGurk SR, Mueser KT, Xie H, Bloch P, DeTore NR, Pashka N, Guarino S, Ruiz A, Elliot C, Gagnon H, Bailey E, Fraser V, Welsh J, Cunningham H, Razzano L, Wolfe R, Drake RE.   +16 more
europepmc   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

The consequences of dismantling community-led HIV programming in Kenya: a call to action from the HEKA programme research partnership in Kenya. [PDF]

BMJ Glob Health
Walimbwa Wambaya J, Ligare F, Wanjiku J, Mwendwa K, Ouma K, Digolo V, Asuri G, Kyalo C, Macharia P, Wambui JM, Noah A, Odhiambo B, Ogalo A, Olango K, Nekesa L, Tabbu S, Tahmo N, Mishra S, Lorway RR, Lazarus L.   +19 more
europepmc   +1 more source

Controlled Peptide Capture and Release in 3D‐Printed Multimaterial Microstructures

Advanced Science, EarlyView.
Two‐photon laser printing of 3D microstructures using a peptide‐containing ink is shown. The microstructures allow for controlled capture and release of target peptides through coiled‐coil interaction with the printed peptide inside the material. Based on these properties, orthogonal capture and stimuli‐mediated release possibilities inside printed ...
Niklas Schwegler, Thomas Heim, Philipp Mainik, Eva Blasco, Franziska Thomas   +4 more
wiley   +1 more source

Joint call to action paper-Pain disparities special issues: Why this, why now? A unified call at a critical time. [PDF]

Health Psychol
Kenney MO, Rassu FS, Bartley EJ, Hirsh AT, Janevic MR, Mathur VA, Merriwether EN.   +6 more
europepmc   +1 more source

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

Advanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang, Jiaqi Zhang, Yuzhi Wang, Yaodong Wang, Peng Lin, Yanling Wang, Zixuan Tang, Jintai Yu, Qin Zhou, Feiyun Cui   +9 more
wiley   +1 more source

Life-Cycle Assessment of an Industrial Recycling Process for Photovoltaic Panels Integrating Mechanical and Air-Assisted Pyrolysis Treatments. [PDF]

Energy Fuels
Ramirez-Cantero J, Garcia-Garcia G, Martín-Lara MÁ, Hernández Z, Pérez A, Calero M.   +5 more
europepmc   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source